Results 51 to 60 of about 206,412 (267)

THE DEVELOPMENT OF APPROACHES FOR OBTAINING AUTOMATED SOLUTION ON THE FORMATION OF THE CURRICULUM

Современные информационные технологии и IT-образование, 2018
Modeling of training processes contributes to obtaining effective solutions of problems in the educational system. One of the most important tasks in the planning of the educational process is computer-aided curriculum design taking into account imposed ...
Anna V. Zykina, Olga N. Kaneva, Viktoria V. Munko   +2 more
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Professional Training of Future Masters of Primary Education to Innovative Activities Through the Prism of a Competence Approach

Journal of Vasyl Stefanyk Precarpathian National University, 2020
The current problems of the advanced system, which were most often used by masters who were studying for innovation, are updated. Theoretical analysis of scientific sources with understanding of the concept of “personal approach” is carried out.
Oksana Tsiuniak
doaj   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

Сurricula plans: competence approach

Polylinguality and Transcultural Practices, 2009
The article focuses on curricula plans and students' role while the principle of complexity and aspect teaching to improve quality of teaching Russian for Foreigners at pre Bachelor's level is put into practice.
T V Shoustikova
doaj  

Formation of non-linguistic competencies in teaching latin

Развитие образования
The methodology of teaching Latin has undergone significant changes in recent years, and traditional approaches do not produce high-quality results. Therefore, the search for new effective methods of teaching this discipline becomes relevant.
Natalya Y. Sivkina, Irina Y. Vashcheva
doaj   +1 more source

Versatile vector tools for efficient protein screening across multiple expression systems

FEBS Open Bio, EarlyView.
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu, Yaqing Liu, Lei Qin, Feng Yu, Qisheng Wang, Yahui Liu   +5 more
wiley   +1 more source

IDENTIFICATION OF INFORMATION AND COMMUNICATION COMPETENCES

Інформаційні технології і засоби навчання, 2010
Article is devoted to identification of information and communication competence and levels of their formation of the future teachers of informatics. It examines the different approaches to the problem of criteria for evaluating competence, describes the
Oleksandr M. Kryvonos
doaj