Results 41 to 50 of about 11,455,528 (298)

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel   +2 more
wiley   +1 more source

Actualization of the concept “competence”, “competency”, “competence approach” in the conditions of integration of science and education

Неофилология, 2015
A short review of use of relevant terms in modern science: competence, competency and competence approach with the aim of defining the author’s relation is given.
Ainagul Bektasovna TUMANOVA
doaj  

The approach to formation of the competence component structure

Высшее образование в России, 2022
This article focuses on the methodical solutions for formation of the basic educational programs, which are constructed on the Federal state educational standards of the third generation.
Efim L. Kon, Vladimir I. Freyman, Aleksandr A. Yuzhakov, Ekaterina M. Kon   +3 more
doaj  

Forecasting Construction Engineering Students’ Learning Outcomes by Means of Computational Pedagogys

Интеграция образования, 2020
Introduction. The prediction of learning outcomes plays an important role in professional training of the future civil engineers. The relevance of the article lies in the lack of a unified approach to predicting the formation of basic professional ...
Juriy A. Tashkinov
doaj   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

RUSSIAN LANGUAGE EDUCATION STRATEGY HOW TO TEACH CHINESE STUDENTS IN THE SOCIAL AND CULTURAL SPACE OF REPUBLIC OF SAKHA (YAKUTIA)

Sovremennye Issledovaniâ Socialʹnyh Problem, 2015
This article presents main problems of the studying Russian as foreign to Chinese students in the social and cultural space of republic of Sakha (Yakutia). There are specific difficulties of learning Chinese students and ways of solving problems.
Sakhaya Nurgunovna Alexandrova
doaj   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

КОМПЕТЕНТНІСНИЙ ПІДХІД ПРИ ВИВЧЕННІ „МАТЕМАТИЧНОЇ ІНФОРМАТИКИ” У ПЕДАГОГІЧНОМУ УНІВЕРСИТЕТІ

Інформаційні технології і засоби навчання, 2010
У статті розглянуто компетентнісний підхід при вивченні математичної інформатики у педагогічному університеті. Особливу увагу звернено на формування професійної педагогічної та навчально-пізнавальну компетентності.
Taras P. Kobylnyk
doaj  

THE DEVELOPMENT OF APPROACHES FOR OBTAINING AUTOMATED SOLUTION ON THE FORMATION OF THE CURRICULUM

Современные информационные технологии и IT-образование, 2018
Modeling of training processes contributes to obtaining effective solutions of problems in the educational system. One of the most important tasks in the planning of the educational process is computer-aided curriculum design taking into account imposed ...
Anna V. Zykina, Olga N. Kaneva, Viktoria V. Munko   +2 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source