Results 111 to 120 of about 16,483,093 (330)

Responsiveness of bovine cumulus-oocyte-complexes (COC) to porcine and recombinant human FSH, and the effect of COC quality on gonadotropin receptor and Cx43 marker gene mRNAs during maturation in vitro [PDF]

open access: yes, 2003
Substantially less development to the blastocyst stage occurs in vitro than in vivo and this may be due to deficiencies in oocyte competence. Although a large proportion of bovine oocytes undergo spontaneous nuclear maturation, less is known about ...
Calder, Michele D   +3 more
core   +4 more sources

Navigating new norms: a systematic review of factors for the development of effective digital tools in higher education

open access: yesFEBS Open Bio, EarlyView.
What factors make for an effective digital learning tool in Higher Education? This systematic review identifies elements of a digital tool that published examples reveal to be features of an engaging and impactful digital tool. A systematic literature search yielded 25 research papers for analysis.
Akmal Arzeman   +4 more
wiley   +1 more source

Parallel Distributed Grammar Engineering for Practical Applications [PDF]

open access: yes, 2011
Based on a detailed case study of parallel grammar development distributed across two sites, we review some of the requirements for regression testing in grammar engineering, summarize our approach to systematic competence and performance profiling, and ...
Bender, Emily M.   +4 more
core  

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

open access: yesFEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon   +6 more
wiley   +1 more source

Reforming Juvenile Justice Systems: Beyond Treatment [PDF]

open access: yes, 2010
Evaluates the role of youth development and cultural competence in the Reclaiming Futures initiative to improve substance abuse interventions as part of juvenile justice reform.

core  

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

open access: yesFEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li   +8 more
wiley   +1 more source

Perceptions of Lecturers, Administrators, and Students About the Workplace as Learning Environment for Undergraduate Medical Students at a National Referral and Teaching Hospital in Uganda

open access: yesAdvances in Medical Education and Practice, 2022
Mike Nantamu Kagawa,1 Sarah Kiguli,2 Hannes Steinberg,3 Mpho Priscilla Jama4 1Department of Obstetrics & Gynaecology, Makerere University, Kampala, Uganda; 2Department of Paediatrics & Child health, Makerere University, Kampala, Uganda; 3Department of ...
Kagawa MN   +3 more
doaj  

Kompetence za poucevanje za trajnostni razvoj na podrocju izobrazevanja uciteljev [PDF]

open access: yes, 2013
Competences are intensively discussed in the context of cross-curricular themes, such as Sustainable Development and Education for Sustainable Development (ESD), especially in light of the United Nations Decade for ESD (2004–2015).
Rauch, Franz, Steiner, Regina
core   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

open access: yesFEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn   +4 more
wiley   +1 more source

An Ontological-based Model for Competences in Sustainable Development Projects: a Case Study for Project’s Commercial Activities [PDF]

open access: yes
The paper presents a project management competencies model, using an ontological approach. The ontology, named PMCatalog, was developed in the framework of the project CONTO, financed by Romanian through the grant 91-037/2007.
Ana Tănăsescu   +3 more
core  

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