Results 121 to 130 of about 1,425,115 (408)

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

open access: yesFEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li   +8 more
wiley   +1 more source

Cultural Competency in Capacity Building [PDF]

open access: yes, 2007
Discusses different capacity building approaches to improving cultural competency that are informed by community participation and multicultural organizational ...
Anushka Fernandopulle   +2 more
core  

Competency-driven benefits realization model for minimization of post-contract transaction costs in design-build (d&b) delivery systems [PDF]

open access: yes, 2017
The construction industry has been struggling with the issue of inconsistent performance with respect to cost of projects, completion time and the delivery of a quality product.
Ganasan, Reventheran   +5 more
core   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

open access: yesFEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn   +4 more
wiley   +1 more source

Developing an artificial intelligence literacy framework: Evaluation of a literacy course for senior secondary students using a project-based learning approach

open access: yesComputers and Education: Artificial Intelligence
The advent of artificial intelligence (AI) in the workplace is pressuring employees to learn how to harness this technology. The goal of promoting AI literacy is to equip educated citizens with the readiness to apply AI.
Siu-Cheung Kong   +2 more
doaj   +1 more source

Implementing the IOM Future of Nursing Report - Part I: How to Dramatically Increase the Formal Education of America's Nursing Workforce by 2020 [PDF]

open access: yes, 2011
Outlines strategies for realizing calls for competency-based curricula; seamless educational progression; more funding for accelerated programs, educational capacity building, and student diversity; and stronger employer ...

core  

Patatin‐domain‐containing (phospho)lipases under control: Mammalian co‐regulators and pathogenic activation mechanisms

open access: yesFEBS Open Bio, EarlyView.
Patatin domain‐containing (phospho)lipases are lipid‐hydrolyzing enzymes central to metabolism, membrane remodeling, and signaling. Their activity relies on precise co‐activation mechanisms involving protein–protein interactions and conformational rearrangements.
Noopur Dubey   +2 more
wiley   +1 more source

Competency-based measures for designing out construction waste: task and contextual attributes [PDF]

open access: green, 2016
Saheed Ajayi   +6 more
openalex   +1 more source

THE APPLICATION OF FUNCTIONAL APPROACH IN STANDAR KOMPETENSI LULUSAN (SKL) UJIAN NASIONAL SMP/MTs OF ENGLISH IN ACADEMIC YEAR 2011 – 2012 [PDF]

open access: yes, 2012
Ujian Nasional (UN) or national examination for the ninth grader of Junior High School has been conducted. Each subject tested has its own competency standard for the graduation or standar kompetensi lulusan (SKL).
Sari, Yohana Ika Harnita
core  

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