Results 261 to 270 of about 1,425,115 (408)

ZNRD2 Mediated Nucleoprotein Aggregation Impairs Respiratory Syncytial Virus Replication

Advanced Science, EarlyView.
During RSV infection, nucleoprotein (N) forms RNA‐bound oligomers. The host protein ZNRD2 binds to these oligomers, promoting their transition into insoluble aggregates. These aggregates simultaneously sequester functional N to restrict viral production and disrupt chaperonin assembly quality control by interfering with ZNRD2's role as an adaptor ...
Haiwu Zhou, Mingbin He, Jinhong Du, Cong Liu, Weiwei Wang, Yuewen Han, Zhifei Li, Yali Qin, Mingzhou Chen   +8 more
wiley   +1 more source

Competency-based curricula in the Eastern Mediterranean Region schools of pharmacy: a framework-informed mixed method study. [PDF]

J Pharm Policy Pract
Al-Ismail M, El-Hage R, Awaisu A, Mahmoud S, Mustafa M, Al-Hamdani M, Mukhalalati B.   +6 more
europepmc   +1 more source

Identifying Spanish Language Competent Physicians: The Diabetes Study of Northern California (DISTANCE)

, 2016
Claudia Chaufan, Andrew J. Karter, Howard H. Moffet, Judy Quan, Melissa M. Parker, Jenna Kruger, Dean Schillinger, Alicia Fernández   +7 more
openalex   +2 more sources

Nurr1 Orchestrates Claustrum Development and Functionality

Advanced Science, EarlyView.
Nurr1 (Nr4a2) is the master transcription factor to control claustrum morphogenesis and cell fate decision postmitotically by inhibiting intracellular G‐protein signaling. Nurr1 deficiency alters the transcriptomic profiles of subcortical claustral neurons into neocortical insular neurons, resulting in defected claustrum development, impaired axonal ...
Kuo Yan, Andrew G. Newman, Pauline Lange, Susanne Müller, Marco Foddis, Stefan Paul Koch, Philipp Böhm‐Sturm, Maron Mantwill, Carsten Finke, Penghui Deng, Melissa Long, Dietmar Schmitz, Victor Tarabykin   +12 more
wiley   +1 more source

Application of mesenchymal stem cells as a vehicle to deliver replication-competent adenovirus for treating malignant glioma

, 2012
Hai Cui, Yongmin Jin, Wenbiao Jin, Zhezhu Han, Mei-Nv Cui, Xuezhe Piao, Xionghu Shen, Songnan Zhang, Honghua Sun   +8 more
openalex   +2 more sources

A GLUTAMATE CYSTEINE LIGASE Gene StGSH1 Regulated by StERF10 Enhanced Glutathione Accumulation and Adaptation to Low Phosphorus Stress in Potato

Advanced Science, EarlyView.
The StERF10‐StGSH1 module coordinates glutathione (GSH) biosynthesis under low‐phosphorus stress. The low‐phosphate‐induced AP2/ERF transcription factor StERF10 directly activates the transcription of StGSH1 and enhances GSH accumulation. Consequently, GSH scavenges reactive oxygen species and provides sulfur for sulfolipid synthesis, facilitating the ...
Xiaocheng Tian, Mingjun Li, Xiaojia Huang, Markus Wirtz, Xiaohui Zheng, Shilong Fan, Jiang Tian, Shaoqun Liu, Zhonghua Liu, Hongbo Zhao   +9 more
wiley   +1 more source

Identifying Core Competencies for Prefieldwork Occupational Therapy Students in Adult Therapy: A Delphi Study With Clinical Therapists. [PDF]

Occup Ther Int
Fan SC, Shao JY, Lu TY, Chi WC, Hung CH.
europepmc   +1 more source

Depletion of Sorcs3 Activates Totipotency in Mouse Embryonic Stem Cells by Modulating Key Signaling Pathways

Advanced Science, EarlyView.
In this article, Shuai and colleagues found that depletion of Sorcs3 could activate totipotency in mESCs, promising bidirectional differentiation potential to embryonic and extraembryonic lineages. The underlying mechanism might be activation of Tfap2c and repression of TGF‐β, PI3K‐AKT, and lysosome pathways.
Wenhao Zhang, Xinyu Mao, Yu He, Qingshen Jia, Yiding Zhao, Xiaomeng Dai, Xiaoyan Li, Shengyi Sun, Xiaoyan Sheng, Dan Ding, Yuan Shi, Qian Gao, Ling Shuai   +12 more
wiley   +1 more source

The Handbook of Competency Mapping: Understanding, Designing and Implementing Competency Models in Organizations

, 2016
Seema Sanghi
semanticscholar   +1 more source

Nursing competency standards in primary health care: an integrative review.

Journal of Clinical Nursing, 2016
E. Halcomb, M. Stephens, J. Bryce, Elizabeth Foley, C. Ashley   +4 more
semanticscholar   +1 more source