Results 51 to 60 of about 14,665,554 (294)
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
A competency-based approach: training specialists with higher education in Kazakhstan
Хабаршы. Психология және социология сериясы, 2016 This article provides a theoretical analysis of the scientific literature on the issue of competence, on the basis of which are provided definitions and applications of the terms competency, competence, competitive, qualification, experience, ability ...
G. G. Ismukhanova, A. R. Sansyzbayeva
doaj +2 more sources
Competing Risks and Multistate Models [PDF]
Clinical Cancer Research, 2013 Abstract Complex clinical endpoints are present in studies in cancer. Especially in studies on hematopoietic stem-cell transplantation (HSCT), various risks exist after HSCT. Patients can experience acute and chronic graft versus host disease (GVHD) or need to undergo immunosuppressive therapy (IST), a relapse can occur, or patients ...
Schmoor, Claudia +3 more
openaire +3 more sources
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Deriving e-assessment from a competency model
, 2008 Self-assessment is a crucial component of learning. Creating effective questions is time-consuming, however, because it may require considerable resources and the skill of critical thinking. Questions need careful construction to accurately represent the
Davis, Hugh +2 more
core +2 more sources
FEBS Letters, EarlyView.Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise +5 more
wiley +1 more source
Lack of consensus among competency ratings of the same occupation: Noise or substance? [PDF]
, 2010 Although rating differences among incumbents of the same occupation have traditionally been viewed as error variance in the work analysis domain, such differences might often capture substantive discrepancies in how incumbents approach their work.
Juan I. Sanchez +8 more
core +1 more source
Metastatic niche shaped by host factors influences disseminated cancer cell fate
FEBS Letters, EarlyView.Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
Education SciencesThe ability to take another person’s perspective is a valuable skill in today’s society, fostering a better understanding of complex issues involving differing viewpoints.
Dina Vasiljuk, Alexandra Budke
doaj +1 more source
A Competence Model for Environmental Education [PDF]
Environment and Behavior, 2013 The goal of environmental education is ultimately to enable a person to strive for and to attain a more ecological way of life. In this article, we begin by distinguishing three forms of environmental knowledge and go on to predict that people’s attitude toward nature represents the force that drives their ecological behavioral engagement.
Nina Roczen +3 more
openaire +1 more source