Results 201 to 210 of about 365,100 (332)

Progress in research of competing endogenous RNAs related to gastrointestinal cancers

, 2017
Yanmei Shi, Yi-Chun Niu, Mingliang Lu, Hua Huang, Jiang Chang, Hai-Yu He   +5 more
openalex   +1 more source

Long Non-coding RNA RP11-395G23.3 Acts as a Competing Endogenous RNA of miR-124-3p to Regulate ROR1 in Anaplastic Thyroid Carcinoma

, 2021
Ancheng Qin, Yi Qian, Yu-Yuan Ma, Yong Jiang, Weifeng Qian   +4 more
openalex   +1 more source

Integrated analysis of competing endogenous RNA networks in peripheral blood mononuclear cells of systemic lupus erythematosus [PDF]

, 2021
Wencong Song, Jie Qiu, Lianghong Yin, Xiaoping Hong, Weier Dai, Donge Tang, Dongzhou Liu, Yong Dai   +7 more
openalex   +1 more source

The Gut Microbiota Regulates Motor Deficits via Butyrate in a Gnal+/− Mouse Model of DYT25 Dystonia

Advanced Science, EarlyView.
The present study provides compelling evidence for a modulatory role of the gut microbiota in the pathology of DYT25 dystonia, and butyrate supplementation alleviates the motor deficits of dystonia in Gnal+/− mice. Abstract Dystonia is the third most common movement disorder, following essential tremor and Parkinson's disease. The underlying mechanisms
Jingya Guo, Seong‐Gook Kang, Kunlun Huang, Tao Tong   +3 more
wiley   +1 more source

LINC01116 Promotes Migration and Invasion of Oral Squamous Cell Carcinoma by Acting as a Competed Endogenous RNA in Regulation of MMP1 Expression [PDF]

, 2022
Yukang Ying, Dong Liu, Yue Zhao, Yuan Zhong, Xuhui Xu, Jun Luo, Zhenxing Zhang   +6 more
openalex   +1 more source

ERM Inhibition Confers Ferroptosis Resistance through ROS‐Induced NRF2 Signaling

Advanced Science, EarlyView.
ERM inhibition disrupts ERM‐actin interactions, elevating ROS and triggering KEAP1 degradation, which stabilizes and activates NRF2. Nuclear NRF2 induces cytoprotective genes, notably HMOX1, enhancing redox buffering and suppressing lipid peroxidation to resist erastin‐induced ferroptosis.
Menghao Qiao, Liqun Zhou, Minhua Zhou, Yu Fang, Haiying Mai, Lingbo Cao, Kun Xu, Yuan Sang, Minyi Chen, Jiewei Huang, Peiyi Huang, Zhipeng Yan, Chao Wang, Zhangshuai Dai, Dichun Huang, Ronghan He, Lijuan Pang, Yunmiao Guo, Ting Gang Chew, Junqi Huang   +19 more
wiley   +1 more source

Identification of competing endogenous RNA networks involved in phrenic nerve stimulation preventing mechanical ventilation induced diaphragm dysfunction. [PDF]

Sci Rep
Zhang M, Li F, Wang M, Li L, Hao W, Duan X, Zhang D.   +6 more
europepmc   +1 more source

Integrated analysis of the lncRNA-associated competing endogenous RNA network in salt sensitivity of blood pressure. [PDF]

Heliyon, 2023
Peng W, Xie Y, Xia J, Qi H, Liu K, Li B, Zhang F, Wen F, Zhang L.   +8 more
europepmc   +1 more source

Additional file 4 of Identification of a ZC3H12D-regulated competing endogenous RNA network for prognosis of lung adenocarcinoma at single-cell level

, 2022
Wenhan Chen, Zhifeng Guo, Jingyang Wu, Guofu Lin, Shaohua Chen, Qinhui Lin, Jiansheng Yang, Yue Xu, Yiming Zeng   +8 more
openalex   +1 more source

HSP70 Interactome‐Mediated Proteolysis Targeting Chimera (HSP70‐PROTAC) for Ferroptosis‐Driven Cancer Treatment

Advanced Science, EarlyView.
This study reports a novel targeted protein degradation strategy termed “HSP70‐PROTAC” that recruits Hsc70 complex to a target protein for inducing degradation. Among them, GDAz‐3 exhibits effective GPX4 degradation activity via UPS/CMA processes, triggering ferroptosis‐driven anticancer activity in vitro and in vivo.
Jinyun Dong, Yulong Li, Hui Liang, Zumei Wu, Shiqun Wang, Yichao Wang, Jieyu Xu, Yanning Lan, Maohua Cai, Guangzhao Pan, Haiyan Yang, Kai Miao, Zhe‐Sheng Chen, Fangfang Tao, Xuelei Ma, Jiang‐Jiang Qin   +15 more
wiley   +1 more source