Results 21 to 30 of about 476,100 (264)

LocalControl: An R Package for Comparative Safety and Effectiveness Research

open access: yesJournal of Statistical Software, 2020
The LocalControl R package implements novel approaches to address biases and confounding when comparing treatments or exposures in observational studies of outcomes.
Nicolas R. Lauve   +4 more
doaj   +1 more source

Imaging of High‐Risk Neuroblastoma: Recommendations From SIOPEN Radiology and Nuclear Medicine Specialty Committees

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Neuroblastoma is the most common extracranial solid tumor in early childhood. Its clinical behavior is highly variable, ranging from spontaneous regression to fatal outcome despite intensive treatment. The International Society of Pediatric Oncology Europe Neuroblastoma Group (SIOPEN) Radiology and Nuclear Medicine Specialty Committees ...
Annemieke Littooij   +11 more
wiley   +1 more source

Modelling competing risks data by a bivariate model with singularity originating from a shock model using the Lehmann family of distributions

open access: yesResearch in Statistics
In this article, a general family of bivariate distributions is used to model competing risks data with dependent causes. The general structure of competing risks data considered here includes ties.
Aakash Agrawal   +2 more
doaj   +1 more source

Exploring Preferences for a Digital Single‐Session Intervention for Adolescent Siblings of Youth With Cancer

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Adolescent siblings of children with cancer are at elevated risk for psychosocial problems. Unfortunately, various barriers such as limited family time and resources, conflicting schedules, and psychosocial staffing constraints at cancer centers hinder sibling access to support.
Christina M. Amaro   +10 more
wiley   +1 more source

Statistical analysis and application of competing risks model with regression

open access: yesCroatian Operational Research Review, 2019
The paper deals with the methods of statistical analysis of dependent competing risks in the presence of covariates. The problem of identification of marginal and joint distributions of competing random variables is recalled and certain ...
Petr Volf
doaj   +1 more source

Novel Genetic Risk Factor Identified for L‐Asparaginase‐Induced Pancreatitis in Pediatric Patients With Cancer

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background L‐asparaginase is a critical component in treatment protocols for pediatric acute lymphoblastic leukemia. Acute pancreatitis reactions can necessitate delays and, in some cases, discontinuation of L‐asparaginase, which compromises outcomes.
Edward J. Raack   +39 more
wiley   +1 more source

Competing Risks In Mortality Analysis [PDF]

open access: yesAnnual Review of Public Health, 1991
In this paper we present a brief review of the concept of competing risks and the statistical methods of mortality analysis including estimation of three types of probability of dying with respect to a particular cause of death. We will describe formulas of estimates for cohort studies medical follow-up studies and analyses of mortality data for a ...
openaire   +2 more sources

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

A genome-wide association study on hematopoietic stem cell transplantation reveals novel genomic loci associated with transplant outcomes

open access: yesFrontiers in Immunology
IntroductionData on genomic susceptibility for adverse outcomes after hematopoietic stem cell transplantation (HSCT) for recipients are scarce.MethodsWe performed a genome wide association study (GWAS) to identify genes associated with survival/mortality,
Albert Rosenberger   +8 more
doaj   +1 more source

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