Results 61 to 70 of about 1,167,728 (343)
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Unemployment Duration: Competing and Defective Risks [PDF]
This paper examines the determinants of unemployment duration in the framework of a competing risks model, where the destination states are employment and inactivity.
John T. Addison, Pedro Portugal
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Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
Molecular Oncology, EarlyView.We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
Application of Competing Risks Models to Credit Risk Assessment
Problemy Zarządzania, 2017 Credit risk arises from the debtor’s possible failure to meet the terms and conditions of the credit contract. As a result, the bank does not receive a particular payment stipulated by the contractual provisions.
Ewa Wycinka
doaj +1 more source
, 2022 Competing risk analysis refers to a special type of survival analysis that aims to correctly estimate marginal probability of an event in the presence of competing events. Traditional methods to describe survival process, such Kaplan Meier product-limit method, are not designed to accommodate the competing nature of multiple causes to the same event ...
openaire +1 more source
Identification of Lagged Duration Dependence in Multiple Spells Competing Risks Models [PDF]
We show non-parametric identification of lagged duration dependence in mixed proportional hazard models for duration data, in the presence of competing risks and consecutive spells.
Guillaume HORNY, Matteo PICCHIO
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Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Competing risks survival modelling of childhood caries [PDF]
The survival of primary molar teeth to caries was investigated using data from a cohort study of 2,654 children aged ~5 years at baseline, undertaken by Cardiff University School of Dentistry in 1999 ...
Stephenson, John
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Decision Tree for Competing Risks Survival Probability in Breast Cancer Study [PDF]
, 2008 Competing risks survival data that comprises of more than one type of event has been used in many applications, and one of these is in clinical study (e.g. in breast cancer study).
Abdul Kudus, Aminuddin +3 more
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