Results 61 to 70 of about 3,890,736 (292)

Omówienie prac nad implementacją dyrektywy 2014/104/UE w Polsce, Hiszpanii i Wielkiej Brytanii [PDF]

open access: yesinternetowy Kwartalnik Antymonopolowy i Regulacyjny, 2016
Artykuł prezentuje wybrane zagadnienia związane z implementacją Dyrektywy Parlamentu Europejskiego i Rady 2014/104/UE z 26 listopada 2014 r. w sprawie niektórych przepisów regulujących dochodzenie roszczeń odszkodowawczych z tytułu naruszenia prawa ...
Jacek Sadurski
doaj   +1 more source

International competition law enforcement: different means, one goal? [PDF]

open access: yes, 2012
This paper addresses one of the intricacies of international competition law enforcement, namely the diversification of legal instruments used for bilateral cooperation.
Demedts, Valerie
core  

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

Is vertical separation a prerequisite to enhancing competition in the South African energy industry?

open access: yesJournal of Economic and Financial Sciences, 2014
Vertical separation is believed to have positive effects in energy sectors where certain phases of the value chain operate under a natural monopoly.
Thembalethu Sithebe, Tshekishi Kolobe
doaj   +1 more source

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

open access: yesFEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman   +2 more
wiley   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

The European Green Deal: shaping environmentally friendly policies under Article 101 TFEU

open access: yesMarket and Competition Law Review, 2020
In the light of the renewed general interest for environmental issues, resulting from the launch of the European Green Deal by President Von Der Leyen, the paper explores how the EU Commission could promote environmental considerations in the ...
Andrea Pezza
doaj   +1 more source

Anti-Competition Regulation [PDF]

open access: yes, 2019
Looking across the long twentieth century, this article tracks the rise and fall of one form of anti-competition regulation: the certificate of public convenience.
Fleming, Anne
core   +1 more source

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

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