Results 61 to 70 of about 743,903 (298)

Is vertical separation a prerequisite to enhancing competition in the South African energy industry?

open access: yesJournal of Economic and Financial Sciences, 2014
Vertical separation is believed to have positive effects in energy sectors where certain phases of the value chain operate under a natural monopoly.
Thembalethu Sithebe, Tshekishi Kolobe
doaj   +1 more source

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

open access: yesMolecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau   +11 more
wiley   +1 more source

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

open access: yesMolecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani   +14 more
wiley   +1 more source

How competitive is cue competition? [PDF]

open access: yesQuarterly Journal of Experimental Psychology, 2019
Cue competition refers to phenomena indicating that learning about the relationship between a cue and an outcome is influenced by learning about the predictive significance of other cues that are concurrently present. In two autoshaping experiments with pigeons, we investigated the strength of competition among cues for predictive value.
Julian Packheiser   +5 more
openaire   +3 more sources

Strategic Polish State Enterprise (SOE) on the list of the largest European companies

open access: yesJournal of Modern Science
Objectives In 2023, only eight Polish enterprises were listed on the Fortune Europe 500, of which seven were classified as State-Owned Enterprises (SOEs). They ranked quite low on the list. The article aims to identify the crucial factors influencing the
Teresa Pakulska   +1 more
doaj   +1 more source

Aberrant expression of nuclear prothymosin α contributes to epithelial‐mesenchymal transition in lung cancer

open access: yesMolecular Oncology, EarlyView.
Nuclear prothymosin α inhibits epithelial‐mesenchymal transition (EMT) in lung cancer by increasing Smad7 acetylation and competing with Smad2 for binding to SNAI1, TWIST1, and ZEB1 promoters. In early‐stage cancer, ProT suppresses TGF‐β‐induced EMT, while its loss in the nucleus in late‐stage cancer leads to enhanced EMT and poor prognosis.
Liyun Chen   +12 more
wiley   +1 more source

Competition [PDF]

open access: yes, 2020
The main objective of this dissertation consists in analyzing the diusive Lotka-Volterra competition model by studying the uniqueness, multiplicity and stability of its component-wise positive steady states, preferably, when the diffusion rates of the species in the inhabiting territory are su ciently small, though some of our results do not require ...
openaire   +1 more source

Attention Competition [PDF]

open access: yesSSRN Electronic Journal, 2011
I present a game-theoretic model where economic competition and attention competition are interdependent. On the one hand the effort to attract consumer attention depends on the value of attention to the firm which depends on the grade of price competition among all perceived firms.
openaire   +3 more sources

ANALYSIS OF FACTORS DEPENDING INNOVATIVE ACTIVITY OF ORGANIZATIONS OF MOSCOW REGION

open access: yesСтатистика и экономика, 2016
The article gives a detailed analysis ofthe views of the organizations surveyedby economic activity. Due to the fact that the share of the manufacturing sector ofthe Moscow region in 2012.
Svetlana N. Zhuravlev
doaj   +1 more source

Early metastasis is characterized by Gr1+ cell dysregulation and is inhibited by immunomodulatory nanoparticles

open access: yesMolecular Oncology, EarlyView.
Breast cancer metastasis is associated with myeloid cell dysregulation and the lung‐specific accumulation of tumor‐supportive Gr1+ cells. Gr1+ cells support metastasis, in part, through a CHI3L1‐mediated mechanism, which can be targeted and inhibited with cargo‐free, polymeric nanoparticles.
Jeffrey A. Ma   +9 more
wiley   +1 more source

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