Results 71 to 80 of about 3,915,899 (313)
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Deterrence in Competition Law [PDF]
, 2009 This paper provides a comprehensive discussion of the deterrence properties of a competition policy regime. On the basis of the economic theory of law enforcement we identify several factors that are likely to affect its degree of deterrence: 1 ...
Buccirossi, Paolo +4 more
core +3 more sources
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
The European Green Deal: shaping environmentally friendly policies under Article 101 TFEU
Market and Competition Law Review, 2020 In the light of the renewed general interest for environmental issues, resulting from the launch of the European Green Deal by President Von Der Leyen, the paper explores how the EU Commission could promote environmental considerations in the ...
Andrea Pezza
doaj +1 more source
Are competition and extrinsic motivation reliable predictors of academic cheating? [PDF]
, 2013 Previous studies suggest that extrinsic motivation and competition are reliable predictors of academic cheating. The aim of the present questionnaire study was to separate the effects of motivation- and competition-related variables on academic cheating ...
Farkas, Dávid +2 more
core +1 more source
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Strategic Polish State Enterprise (SOE) on the list of the largest European companies
Journal of Modern ScienceObjectives In 2023, only eight Polish enterprises were listed on the Fortune Europe 500, of which seven were classified as State-Owned Enterprises (SOEs). They ranked quite low on the list. The article aims to identify the crucial factors influencing the
Teresa Pakulska +1 more
doaj +1 more source
ANALYSIS OF FACTORS DEPENDING INNOVATIVE ACTIVITY OF ORGANIZATIONS OF MOSCOW REGION
Статистика и экономика, 2016 The article gives a detailed analysis ofthe views of the organizations surveyedby economic activity. Due to the fact that the share of the manufacturing sector ofthe Moscow region in 2012.
Svetlana N. Zhuravlev
doaj +1 more source
The first automated negotiating agents competition (ANAC 2010)
, 2011 Motivated by the challenges of bilateral negotiations between people and automated agents we organized the first automated negotiating agents competition (ANAC 2010).
Baarslag, Tim +4 more
core +1 more source
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
Molecular Oncology, EarlyView.We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source