Results 61 to 70 of about 1,253,967 (267)
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
The European Green Deal: shaping environmentally friendly policies under Article 101 TFEU
Market and Competition Law Review, 2020 In the light of the renewed general interest for environmental issues, resulting from the launch of the European Green Deal by President Von Der Leyen, the paper explores how the EU Commission could promote environmental considerations in the ...
Andrea Pezza
doaj +1 more source
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Is vertical separation a prerequisite to enhancing competition in the South African energy industry?
Journal of Economic and Financial Sciences, 2014 Vertical separation is believed to have positive effects in energy sectors where certain phases of the value chain operate under a natural monopoly.
Thembalethu Sithebe, Tshekishi Kolobe
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
The internal market's dioskouroi: free movement and competition law [PDF]
, 2017 This talk, delivered on the occasion of the presentation of the journal "Market and Competition Law Reviews", explores the role of the rules on free movement and on competition law in the establishment and functioning of the EU internal ...
ARENA, AMEDEO
core
ANALYSIS OF FACTORS DEPENDING INNOVATIVE ACTIVITY OF ORGANIZATIONS OF MOSCOW REGION
Статистика и экономика, 2016 The article gives a detailed analysis ofthe views of the organizations surveyedby economic activity. Due to the fact that the share of the manufacturing sector ofthe Moscow region in 2012.
Svetlana N. Zhuravlev
doaj +1 more source
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source