Results 101 to 110 of about 2,429,852 (338)

Molecular evolution between chemistry and biology [PDF]

open access: yesEuropean Biophysics Journal, 2018
Biological evolution is reduced to three fundamental processes in the spirit of a minimal model: (i) Competition caused by differential fitness, (ii) cooperation of competitors in the sense of symbiosis, and (iii) variation introduced by mutation understood as error-prone reproduction. The three combinations of two fundamental processes each, ([Formula:
openaire   +3 more sources

Contrasting impacts of competition on ecological and social trait evolution in songbirds

open access: yesPLoS Biology, 2018
Competition between closely related species has long been viewed as a powerful selective force that drives trait diversification, thereby generating phenotypic diversity over macroevolutionary timescales.
J. Drury   +5 more
semanticscholar   +1 more source

An Overview of Agent-Based Models in Plant Biology and Ecology.

open access: yesAnnals of Botany, 2020
Agent-based modeling (ABM) has become an established methodology in many areas of biology, ranging from the cellular to the ecological population and community levels. In plant science, two different scales have predominated in their use of ABM.
Bo Zhang, D. DeAngelis
semanticscholar   +1 more source

MET variants with activating N‐lobe mutations identified in hereditary papillary renal cell carcinomas still require ligand stimulation

open access: yesMolecular Oncology, EarlyView.
MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin   +14 more
wiley   +1 more source

Ceteris Paribus Laws [PDF]

open access: yes, 2011
Laws of nature take center stage in philosophy of science. Laws are usually believed to stand in a tight conceptual relation to many important key concepts such as causation, explanation, confirmation, determinism, counterfactuals etc.
Hüttemann, Andreas   +2 more
core   +1 more source

Local cellular neighborhood controls proliferation in cell competition

open access: yesMolecular Biology of the Cell, 2017
Cell competition is a quality-control mechanism through which tissues eliminate unfit cells. Automated microscopy with deep-learning image analysis was used to measure single-cell behavior during competition.
Anna Bove   +5 more
semanticscholar   +1 more source

Peripheral blood proteome biomarkers distinguish immunosuppressive features of cancer progression

open access: yesMolecular Oncology, EarlyView.
Immune status significantly influences cancer progression. This study used plasma proteomics to analyze benign 67NR and malignant 4T1 breast tumor models at early and late tumor stages. Immune‐related proteins–osteopontin (Spp1), lactotransferrin (Ltf), calreticulin (Calr) and peroxiredoxin 2 (Prdx2)–were associated with systemic myeloid‐derived ...
Yeon Ji Park   +6 more
wiley   +1 more source

Towards the Development of an Evolutionarily Valid Domain-Specific Risk-Taking Scale

open access: yesEvolutionary Psychology, 2007
From an evolutionary perspective, human risk-taking behaviors should be viewed in relation to evolutionarily recurrent survival and reproductive problems.
Daniel J. Kruger   +2 more
doaj   +1 more source

Auxotrophy to Xeno-DNA: an exploration of combinatorial mechanisms for a high-fidelity biosafety system for synthetic biology applications

open access: yesJournal of Biological Engineering, 2018
Background Biosafety is a key aspect in the international Genetically Engineered Machine (iGEM) competition, which offers student teams an amazing opportunity to pursue their own research projects in the field of Synthetic Biology.
Christopher M. Whitford   +9 more
doaj   +1 more source

Grand challenges for the spatial information community

open access: yesJournal of Spatial Information Science, 2020
The spatial information (SI) community has an opportunity to address major societal and scientific problems including public health, climate change, air pollution, transportation, and others. Beyond the significant contributions made by the SI community,
Leye Wang, Ouri Wolfson
doaj   +1 more source

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