Results 81 to 90 of about 766,564 (291)

Effects of temporal variability on rare plant persistence in annual [PDF]

, 2004
Traditional conservation biology regards environmental fluctuations as detrimental to persistence, reducing long-term average growth rates and increasing the probability of extinction.
Levine, J.M., Rees, M.
core  

Supplementary feeding increases nestling feather corticosterone early in the breeding season in house sparrows [PDF]

, 2017
Several studies on birds have proposed that a lack of invertebrate prey in urbanized areas could be the main cause for generally lower levels of breeding success compared to rural habitats.
De Neve, Liesbeth, Fairhurst, Graham D, Lens, Luc, Peach, Will J, Salleh Hudin, Noraine, Strubbe, Diederik, Vangestel, Carl   +6 more
core   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Genetic draft, selective interference, and population genetics of rapid adaptation [PDF]

, 2013
To learn about the past from a sample of genomic sequences, one needs to understand how evolutionary processes shape genetic diversity. Most population genetic inference is based on frameworks assuming adaptive evolution is rare.
Neher, Richard A.
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Lost in translation? – Caveat to the application of the voter model in ecology and evolutionary biology

Science Progress, 2023
The voter model is a paradigmatic model of competition between alternative states within groups. Its properties have been intensively studied in statistical physics.
Beáta Oborny
doaj   +1 more source

Seed production of barnyardgrass (Echinochloa crus-galli) in response to time of emergence in cotton and rice [PDF]

, 2012
The spread of herbicide resistance in barnyardgrass (Echinochloa crus-galli (L.) Beauv.) poses a serious threat to crop production in the southern United States.
Assemat, Blackshaw, Bosnic, Chism, Clay, Cowan, Holm, J. K. NORSWORTHY, K. L. SMITH, Keeley, Lindquist, M. V. BAGAVATHIANNAN, Mitich, Norris, P. NEVE, Rahn, Slaton, Toler   +17 more
core   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

An integrated engineering worldview of synthetic biology education through the lens of webinar based pedagogy

Frontiers in Bioengineering and Biotechnology
Synthetic biology is an interdisciplinary field that brings together engineering and biology concepts alongside the arts and social sciences to develop solutions to pressing problems in our world.
Iain George, Paul Ross, Yixian Yang, Martin Holub, Nina Rajpurohit, Ibrahim Aldulijan, Jacob Beal, Alejandro Vignoni, Dennis Mishler, Dennis Mishler   +9 more
doaj   +1 more source

Towards the Development of an Evolutionarily Valid Domain-Specific Risk-Taking Scale

Evolutionary Psychology, 2007
From an evolutionary perspective, human risk-taking behaviors should be viewed in relation to evolutionarily recurrent survival and reproductive problems.
Daniel J. Kruger, X.T. Wang, Andreas Wilke   +2 more
doaj   +1 more source