Results 71 to 80 of about 766,564 (291)

AAA+ protein unfoldases—the Moirai of the proteome

FEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

Cheater-altruist synergy in immunopathogenic ecological public goods games

, 2017
Much research has focused on the deleterious effects of free-riding in public goods games, and a variety of mechanisms that suppresses cheating behaviour. Here we argue that under certain conditions cheating behaviour can be beneficial to the population.
Morsky, Bryce, Vural, Dervis Can
core   +1 more source

Ecosystem size predicts eco-morphological variability in a postglacial diversification [PDF]

, 2017
Identifying the processes by which new phenotypes and species emerge has been a long-standing effort in evolutionary biology. Young adaptive radiations provide a model to study patterns of morphological and ecological diversification in environmental ...
Adams, Colin E., Elmer, Kathryn R., Hooker, Oliver E., Recknagel, Hans   +3 more
core   +1 more source

Cultivation of Synthetic Biology with the iGEM Competition

Journal of Advanced Computational Intelligence and Intelligent Informatics, 2013
The main goal of synthetic biology is to create new biological modules that augment or modify the behavior of living organisms in performing different tasks. These modules are useful in a wide range of applications, such as medicine, agriculture, energy and environmental remediation.
Thamamongood, Thiprampai, Lim, Nathaniel Z.L., Ho, Trevor Y.H., Ayukawa, Shotaro, Kiga, Daisuke, Chow, King Lau   +5 more
openaire   +2 more sources

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

The forestecology R package for fitting and assessing neighborhood models of the effect of interspecific competition on the growth of trees

Ecology and Evolution, 2021
Neighborhood competition models are powerful tools to measure the effect of interspecific competition. Statistical methods to ease the application of these models are currently lacking.
Albert Y. Kim, David N. Allen, Simon P. Couch   +2 more
doaj   +1 more source

Competencia entre mitílidos en el intermareal rocoso de La Lobería, Río Negro, Argentina [PDF]

, 2016
Competitive interactions between individuals from a single or different species can regulate population densities and individual growth. Two mussel species, Brachidontes rodriguezii and Perumytilus purpuratus coexist in the rocky intertidal zone of La ...
Arribas, Lorena Pilar, Bagur Creta, Maria, Gutierrez, Jorge Luis Ceferino, Palomo, Maria Gabriela, Soria, Sabrina Andrea   +4 more
core  

Functional relevance of the newly evolved sperm dynein intermediate chain multigene family in Drosophila melanogaster males. [PDF]

, 2012
In many animal species, traits associated with male fitness evolve rapidly. Intersexual conflict and male-male competition have been suggested to drive this rapid evolution.
Abbassi, Mashya, Do, Tiffanie, Ranz, José M, Yeh, Shu-Dan   +3 more
core   +2 more sources

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Comparison between Effects of Retroactivity and Resource Competition upon Change in Downstream Reporter Genes of Synthetic Genetic Circuits

Life, 2019
Reporter genes have contributed to advancements in molecular biology. Binding of an upstream regulatory protein to a downstream reporter promoter allows quantification of the activity of the upstream protein produced from the corresponding gene.
Takefumi Moriya, Tomohiro Yamaoka, Yuki Wakayama, Shotaro Ayukawa, Zicong Zhang, Masayuki Yamamura, Shinji Wakao, Daisuke Kiga   +7 more
doaj   +1 more source