Results 51 to 60 of about 766,564 (291)

Verification of systems biology research in the age of collaborative competition [PDF]

Nature Biotechnology, 2011
Collaborative competitions in which communities of researchers compete to solve challenges may facilitate more rigorous scrutiny of scientific results.
Meyer Pablo, Alexopoulos Leonidas G, Bonk Thomas, Califano Andrea, Cho Carolyn R, de la Fuente Alberto, de Graaf David, Hartemink Alexander J, Hoeng Julia, Ivanov Nikolai V, Koeppl Heinz, Linding Rune, Marbach Daniel, Norel Raquel, Peitsch Manuel C, Rice J Jeremy, Royyuru Ajay, Schacherer Frank, Sprengel Joerg, Stolle Katrin, Vitkup Dennis, Stolovitzky Gustavo   +21 more
openaire   +2 more sources

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Shared Transcriptional Machinery at Homologous Alleles Leads to Reduced Transcription in Early Drosophila Embryos

Frontiers in Cell and Developmental Biology, 2022
The mechanism by which transcriptional machinery is recruited to enhancers and promoters to regulate gene expression is one of the most challenging and extensively studied questions in modern biology.
Hao Deng, Bomyi Lim
doaj   +1 more source

Proceedings of the COST SUSVAR/ECO-PB Workshop on organic plant breeding strategies and the use of molecular markers [PDF]

, 2005
In many countries,national projects are in progress to investigate the sustainable low-input approach.In the present COST network,these projects are coordinated by means of exchange of materials,establishing common methods for assessment and statistical ...

core  

Increase of an introduced bird competitor in old-growth forest associated with restoration [PDF]

, 2012
Many successful invasions involve long initial periods in which the invader exists at low densities followed by sudden population increases. The reasons for such time-lags remain poorly understood.
Cann, Rebecca L., Freed, Leonard A.
core   +2 more sources

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Competition between Silicifiers and Non-silicifiers in the Past and Present Ocean and Its Evolutionary Impacts

Frontiers in Marine Science, 2018
Competition is a central part of the evolutionary process, and silicification is no exception: between biomineralized and non-biomineralized organisms, between siliceous and non-siliceous biomineralizing organisms, and between different silicifying ...
Katharine R. Hendry, Alan O. Marron, Flora Vincent, Daniel J. Conley, Daniel J. Conley, Marion Gehlen, Federico M. Ibarbalz, Bernard Quéguiner, Chris Bowler   +8 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Responsible and safe innovation in education: an iGEM showcase

Journal of Responsible Innovation
This paper showcases a project involved in the international Genetically Engineered Machines (iGEM) competition – a competition dedicated to the advancement of synthetic biology – executed at Delft University of Technology, the Netherlands.
Britte Bouchaut, Lotte Asveld
doaj   +1 more source

The relevance of non-formal Biology Olympiad training for upper secondary school students

LUMAT, 2018
Science competitions, such as the International Biology Olympiad, are non-formal education targeted to upper secondary school students with high abilities.
Justus Mutanen, Maija Aksela
doaj   +1 more source