Results 21 to 30 of about 2,499,667 (343)

An Effective Sign Switching Dark Energy: Lotka–Volterra Model of Two Interacting Fluids

Universe, 2023
One of the recent attempts to address the Hubble and S8 tensions is to consider that the Universe started out not as a de Sitter-like spacetime, but rather anti-de Sitter-like. That is, the Universe underwent an “AdS-to-dS” transition at some point.
Yen Chin Ong
doaj   +1 more source

Ethical framework on risk governance of synthetic biology

Journal of Biosafety and Biosecurity, 2023
Synthetic biology is an emerging multidisciplinary field that aims to design and construct new biological systems not found in nature. Whereas synthetic biology may yield tremendous benefits, it may also pose substantial risks to human health and the ...
Liao Bohua, Wang Yuexin, Ou Yakun, Zuo Kunlan, Liu Huan, Lei Ruipeng   +5 more
doaj   +1 more source

iGEM 2021: A Year in Review

BioDesign Research, 2022
The international Genetically Engineered Machine (iGEM) Foundation has continued to promote synthetic biology education throughout its 2021 competition.
Hannah Moon
doaj   +1 more source

Stem cell lineage survival as a noisy competition for niche access [PDF]

Proceedings of the National Academy of Sciences of the United States of America, 2020
Significance What defines the number and dynamics of the stem cells that generate and renew biological tissues? Although several molecular markers have been described to predict stem cell potential, we propose a complementary approach that mathematically
B. Corominas-Murtra, C. Scheele, Kasumi Kishi, S. I. Ellenbroek, B. Simons, J. van Rheenen, É. Hannezo   +6 more
semanticscholar   +1 more source

The evolution of sperm morphometry in pheasants [PDF]

, 2007
Postcopulatory sexual selection is thought to be a potent evolutionary force driving the diversification of sperm shape and function across species. In birds, insemination and fertilisation are separated in time and sperm storage increases the duration
Birkhead, T.R., Immler, S., Lesobre, L., Roman, Y., Saint-Jalme, M., Sorci, G.   +5 more
core   +3 more sources

Recent Progress in European Advanced Therapy Medicinal Products and Beyond

Frontiers in Bioengineering and Biotechnology, 2018
Cell- and gene-based therapies form one of the pillars of regenerative medicine. They have the potential to transform quality of life and improve the health status of patients with genetic and cellular defects, including genetic diseases ...
Tracy T. L. Yu, Tracy T. L. Yu, Tracy T. L. Yu, Pravesh Gupta, Vincent Ronfard, Alain A. Vertès, Yves Bayon   +6 more
doaj   +1 more source

Modeling viral coevolution: HIV multi-clonal persistence and competition dynamics [PDF]

, 2005
The coexistence of different viral strains (quasispecies) within the same host are nowadays observed for a growing number of viruses, most notably HIV, Marburg and Ebola, but the conditions for the formation and survival of new strains have not yet been ...
Altfeld, Bagnoli, Bello, Blackard, Burch, Celada, Chao, Costa, De Boer, De Boer, Eigen, Eigen, F. Bagnoli, Franz, Galvani, Gerhardt, Gog, Haaft, Ho, Jenkins, Jetzt, Kijak, Krempl, L. Sguanci, Levy, Lin, Lio, Mansky, Miller, Neumann, P. Liò, Pantaleo, Parkin, Perelson, Perelson, Ramos, Revilla, Schnell, Shankarappa, Wei, Wiegel, Wodarz1, Yang, Zanotto   +43 more
core   +2 more sources

Autoamplification and Competition Drive Symmetry Breaking: Initiation of Centriole Duplication by the PLK4-STIL Network

iScience, 2018
Summary: Centrioles, the cores of centrosomes and cilia, duplicate every cell cycle to ensure their faithful inheritance. How only a single procentriole is produced on each mother centriole remains enigmatic.
Marcin Leda, Andrew J. Holland, Andrew B. Goryachev   +2 more
doaj   +1 more source

Synthesizing a novel genetic sequential logic circuit: a push‐on push‐off switch

Molecular Systems Biology, 2010
Design and synthesis of basic functional circuits are the fundamental tasks of synthetic biologists. Before it is possible to engineer higher‐order genetic networks that can perform complex functions, a toolkit of basic devices must be developed.
Chunbo Lou, Xili Liu, Ming Ni, Yiqi Huang, Qiushi Huang, Longwen Huang, Lingli Jiang, Dan Lu, Mingcong Wang, Chang Liu, Daizhuo Chen, Chongyi Chen, Xiaoyue Chen, Le Yang, Haisu Ma, Jianguo Chen, Qi Ouyang   +16 more
doaj   +1 more source

The Field of Cell Competition Comes of Age: Semantics and Technological Synergy

Frontiers in Cell and Developmental Biology, 2022
Stem cells experience many selective pressures which shape their cellular populations, potentially pushing them to skew towards dominance of a few break-through clones. An evolutionarily conserved answer to curb these aberrant selective pressures is cell
Kieran Maheden, Vivian Weixuan Zhang, Nika Shakiba   +2 more
doaj   +1 more source