Results 41 to 50 of about 4,262,535 (256)
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Advances in Difference Equations, 2021 This study investigates the dynamical behavior of a ratio-dependent Lotka–Volterra competitive-competitive-cooperative system with feedback controls and delays. Compared with previous studies, both ratio-dependent functional responses and time delays are
Ahmadjan Muhammadhaji +2 more
doaj +1 more source
Nematode Predation and Competitive Interactions Affect Microbe-Mediated Phosphorus Dynamics
mBio, 2022 Nematode predation plays an essential role in determining changes in the rhizosphere microbiome. These changes affect the local nutrient balance and cycling of essential nutrients by selectively structuring interactions across functional taxa in the ...
Jie Zheng +7 more
doaj +1 more source
Structural and biochemical analysis of a B12 superbinder
FEBS Letters, EarlyView.BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
Essays on the behavioral foundations of competitive interaction [PDF]
, 2013 The competitive dynamics perspective offers a micro-level, dynamic view of market competition. It is axiomatic for students of competitive dynamics that competitive actions and interactions are shaped by the boundedly rational decision making of ...
Luoma, Jukka
core +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Artificial molecular machines and motors—Design and control of nanoscale motion
FEBS Letters, EarlyView.Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley +1 more source
Boom-bust population dynamics increase diversity in evolving competitive communities
Communications Biology, 2021 Michael Doebeli et al. introduce a discrete-time competition model with multi-dimensional evolving phenotypes to explore the effect of boom-bust population dynamics on the evolution of diversity.
Michael Doebeli +2 more
doaj +1 more source
Economic integration and the dynamics of firms’ competitive behavior
, 2012 We investigate the evolution of firms’ competitive behavior in the EU by studying the dynamics of firms’ price-cost margins (PCMs) across four countries (France, Italy, Poland and Sweden), in three manufacturing and three services industries for around ...
Carlo Altomonte +5 more
core +1 more source