Results 51 to 60 of about 133,544 (263)

Dynamic peer-to-peer competition [PDF]

Physica A: Statistical Mechanics and its Applications, 2010
The dynamic behavior of a multiagent system in which the agent size $s_{i}$ is variable it is studied along a Lotka-Volterra approach. The agent size has hereby for meaning the fraction of a given market that an agent is able to capture (market share). A Lotka-Volterra system of equations for prey-predator problems is considered, the competition factor
Caram, L. F., Caiafa, C. F., Proto, A. N., Ausloos, Marcel   +3 more
openaire   +2 more sources

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

Mixed‐class J‐domain protein scaffolds promote expanded aggregate handling and multivalent Hsp70 engagement during functional disaggregase assembly

FEBS Letters, EarlyView.
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

The Container Market in Baltic Ports: Market Share Development and Trend Forecasting

Big Data and Cognitive Computing
This study examines the evolution of container throughput and competitive market-share dynamics in the three principal Baltic container ports—Klaipeda, Riga, and Tallinn—during the period 2005–2024 and provides baseline forecasts to 2030.
Diana Šateikienė, Jurga Kučinskienė
doaj   +1 more source

Vector interaction model of factors of retailers` competitiveness [PDF]

Marketing i Menedžment Innovacij, 2013
The aim of the article. The aim of the article is to develop scientific and methodical approach to the modeling and analysis of complex elements, settings, and the phase trajectories of competition in the market.
T.O. Zagornaya
doaj  

Higher-order interactions mitigate direct negative effects on population dynamics of herbaceous plants during succession

Environmental Research Letters, 2020
Plant succession is regulated by a combination of abiotic and biotic factors. However, previous studies of biotic drivers have focused overwhelmingly on direct pairwise species interactions, ignoring the likely prevalent higher-order interactions (HOIs ...
Junli Xiao, Yuanzhi Li, Chengjin Chu, Youshi Wang, Scott J Meiners, Daniel B Stouffer   +5 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Competitive Dynamics of Market Entry: Scale and Survival [PDF]

Management and Economics Review, 2017
Market entry is the essence of strategy and is largely viewed as a dichotomous event: entry or no entry. What has not been acknowledged is the uniqueness of each market entry.
John W. UPSON, Mariana S. SANCHEZ, William J. SMITH   +2 more
doaj  

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source