Results 41 to 50 of about 507,489 (304)

Stackelberg-Nash Equilibrium in competitive facility location game among a franchisor and two investors [PDF]

open access: yesمجله مدل سازی در مهندسی, 2019
In the competitive location problems, the matter of the optimal location of single or multiple facilities are in a condition in which competitors exist as well.
Abbas Kari Majidabad   +2 more
doaj   +1 more source

The trade-off between corporate social responsibility and competitive advantage: a biform game model

open access: yesTechnological and Economic Development of Economy, 2022
This paper uses a biform game model to study firms’ trade-offs between corporate social responsibility (CSR) and competitive advantage. We focus on the context in which a competitive advantage may lead to a non-profitable scenario.
Xiaoyang Zhao, Justin Tan, Shuxin Zhong
doaj   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Existence for Competitive Equilibrium by Means of Generalized Quasivariational Inequalities

open access: yesAbstract and Applied Analysis, 2013
A competitive economic equilibrium model integrated with exchange, consumption, and production is considered. Our goal is to give an existence result when the utility functions are concave, proper, and upper semicontinuous.
I. Benedetti, M. B. Donato, M. Milasi
doaj   +1 more source

Two competitive products diffusion in heterogeneous consumer social networks with repeat purchase

open access: yesAdvances in Difference Equations, 2019
This paper studies the dynamics of two competitive products diffusion in heterogeneous consumer social networks with repeat purchase. We demonstrate a threshold for the diffusion rate above which a single product can persistently diffuse in heterogeneous
Qiwei Huang, Yulin Zhang
doaj   +1 more source

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

open access: yesFEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti   +3 more
wiley   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

open access: yesFEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen   +9 more
wiley   +1 more source

On the Zero-Hopf Bifurcation of the Lotka–Volterra Systems in R 3

open access: yesMathematics, 2020
Here we study 3-dimensional Lotka–Volterra systems. It is known that some of these differential systems can have at least four periodic orbits bifurcating from one of their equilibrium points.
Maoan Han, Jaume Llibre, Yun Tian
doaj   +1 more source

Mechanochemical Synthesis and Characterization of Nanostructured ErB4 and NdB4 Rare‐Earth Tetraborides

open access: yesAdvanced Engineering Materials, Volume 27, Issue 6, March 2025.
ErB4 and NdB4 nanostructured powders are produced by mechanochemical synthesis. 5 h mechanical alloying and 4 M HCl acid leaching are used in the production. ErB4 and NdB4 powders exhibit maximum magnetization of 0.4726 emu g−1 accompanied with an antiferromagnetic‐to‐paramagnetic phase transition at about TN = 18 K and 0.132 emu g−1 with a maximum at ...
Burçak Boztemur   +5 more
wiley   +1 more source

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