Results 61 to 70 of about 318,502 (328)

Mechanism Design with Strategic Mediators

open access: yes, 2015
We consider the problem of designing mechanisms that interact with strategic agents through strategic intermediaries (or mediators), and investigate the cost to society due to the mediators' strategic behavior. Selfish agents with private information are
Babaioff, Moshe   +2 more
core   +1 more source

Why human connection is the true metric of research success

open access: yesFEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan   +3 more
wiley   +1 more source

Employment Generation and Poverty Alleviation through SME Cluster Development in Bangladesh [PDF]

open access: yes, 2015
SME Cluster Development could be an emerging force of entrepreneurship development, employment generation and poverty alleviation for any least developed country like Bangladesh.
ABDIN, Md. Joynal, BEGUM, Arfin Ara
core   +2 more sources

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

open access: yesFEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer   +7 more
wiley   +1 more source

The competitive facility location based on the spatial interaction model

open access: yesمدیریت تولید و عملیات, 2012
In this paper, a nonlinear model for locating service facilities is introduced in a competitive ‎ region. In the proposed model the factors of travel time, quality of service facilities and price ‎ are considered that are the most important effective ...
naeme zarrinpoor, maryam esmaeeli
doaj  

Solution of Bi-objective Competitive Facility Location Problem Using Parallel Stochastic Search Algorithm [PDF]

open access: yes, 2015
Proceedings of: Second International Workshop on Sustainable Ultrascale Computing Systems (NESUS 2015). Krakow (Poland), September 10-11, 2015.The work has been partially supported by EU under the COST Action IC1305 “Network for Sustainable Ultrascale ...
Lancinskas, Algirdas   +2 more
core   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

The C‐terminal region of KIF26B is indispensable for nephron progenitor condensation and kidney formation in mice

open access: yesFEBS Open Bio, EarlyView.
KIF26B plays an important role in kidney development. We engineered mice lacking the C‐terminal region of KIF26B and found severe kidney defects, including bilateral renal agenesis, similar to full Kif26b knockout mice. The mutation disrupted nephron progenitor condensation and reduced Gdnf‐Wnt11 signaling, showing that the KIF26B C‐terminal region is ...
Yuta Yamamura   +19 more
wiley   +1 more source

On a branch-and-bound approach for a Huff-like Stackelberg location problem [PDF]

open access: yes
Modelling the location decision of two competing firms that intend to build a new facility in a planar market can be done by a Huff-like Stackelberg location problem.
Fernández, J.   +3 more
core   +3 more sources

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

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