Results 61 to 70 of about 317,143 (313)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

The Pricing and Competitive Strategies of U.S. Airlines

, 1989
This paper argues that price competition is inevitable in the airline markets because passenger air service is a "search good." For the same reason, the optimal long run competitive strategy for the airline is "cost leadership," although qualitative ...
Douglas, Evan J.
core   +1 more source

Examination of effects of competitive strategies on the e-commerce companies in terms of achieving sustainable competitive advantage [PDF]

, 2019
E-commerce brings companies and customers together in an exchange market environment, beyond any physical, cultural, and legal boundaries, and on an unimaginable scale, which was considered to be technically impossible before.
Adıgüzel, Zafer, Zafer Adiguzel
core   +1 more source

Mutualism: Mutually Beneficial Cooperation between Competing Firms (Cases of Russian Companies)

Современная конкуренция
This article examines the phenomenon of positive cooperation between competing firms (mutualism) – it documents and discusses previously unexplored cases of this type of behavior by Russian companies.
Andrey Yu. Yudanov
doaj   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Do competitive strategies moderate the relationship between learning organization and performance of higher education institutions? [PDF]

, 2019
This study seeks to examine the moderating effect of competitive strategies which include cost leadership, differentiation and focus strategies in the relationship between learning organization and organizational performance of Yemeni HEIs.
Arshad, Darwina, Habtoor, Ammar Saleh, Hassan, Hazlinda   +2 more
core  

Managing and marketing tourist destinations: Strategies to gain a competitive edge

, 2011
Destination marketing is more challenging than other goods and services. The basis of competitive advantage shifts from tourism resources only (destination marketing) to a location-based or city-wide integrated management (place marketing). In this book,
Kozak, M., Baloglu, S.
core   +1 more source

Development of Competitive Strategies in the "Clarinet" (Clustering and Networking) Model in Private Schools to Increase Student Interest

Jurnal Kependidikan
This research aims to describe the framework for developing competitive strategies for schools using “Clarinet” (clustering and networking) models, as well as to assess the feasibility of the development guide for competitive strategies in “Clarinet ...
Penta Karuni Hapsari, Listyani Listyani, Bambang Ismanto   +2 more
doaj   +1 more source