Results 61 to 70 of about 5,445,100 (248)

The market for non-alcoholic wine in Germany – Structural analysis and implications for competitive strategies

Wine Economics and Policy
Non-alcoholic wines have become increasingly important in recent years in Germany. A constant stream of new market players and products is evidence of a dynamic market development and for the creation of a new branch in the highly competitive wine sector.
Frederik Nikolai Schulz, Jon H. Hanf
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Strategies for appropriate technology and competitive performance in infrastructure construction [PDF]

, 1994
Earlier research developed theoretically-based aggregate metrics for technology strategy and used them to analyze California bridge construction firms (Hampson, 1993). Determinants of firm performance, including trend in contract awards, market share and
Hampson, Keith D., Tatum, C. Bob
core  

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Competitive Strategies Employed and Performance of Tea Growers in the Western Zone of Kenya; A Case Study of Unilever Tea Kenya Limited

, 2022
: The study aims at determining the competitive strategies employed and performance of Unilever Tea Kenya Limited (UTKL). Competitive strategies encompass the overall organizational moves and approaches, which a firm possesses and is undertaking as a ...
Dr. Jane Queen Omwenga, Mercy Nyaboke Onderi   +1 more
core   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Modeling Effective Budgeting and Production For Sustainable Competitive Advantage: Evidence from Kufa Cement Factory, Iraq

Foundations of Management
The current study aims at conceptualizing time-driven activity-based budgeting and cleaner production (CP) techniques and their integration in achieving sustainable competitive advantage by applying them at Kufa Cement Factory, an economic unit under the
ALAWAED Husam Muhammed Ali, AL-KAWAZ Salah Mahdi Jawad, ABBAS Ali Abdulhassan, ALNASRAWI Salam Adil Abbas   +3 more
doaj   +1 more source

Frequency of interaction-mediated triggering of antibiotic production among soil bacteria

Frontiers in Microbiology, 2014
Certain bacterial species produce antimicrobial compounds only in the presence of a competing species. However little is known on the frequency of interaction-mediated induction of antibiotic compound production in natural communities of soil bacteria ...
Olaf eTyc, Marlies evan den Berg, Saskia eGerards, Johannes evan Veen, Wietse eDe Boer, Jos M Raaijmakers, Paolina eGarbeva   +6 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source