Results 81 to 90 of about 5,445,100 (248)
Molecular Oncology, EarlyView.This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu +3 more
wiley +1 more source
Estratégias Competitivas para Empresas de Rochas Ornamentais na Região Metropolitana do Rio de Janeiro [PDF]
Anuário do Instituto de Geociências, 2005 The strategy to accelerate the development of mining-beneficiationtechnology- competitivity management of dimension stone companies involves various analysis and alternative methodologies.
Claudio Margueron, Edson Farias Mello
doaj
Diversity of bacterial small RNAs drives competitive strategies for a mutual chaperone. [PDF]
Nat Commun, 2022 Roca J, Santiago-Frangos A, Woodson SA.
europepmc +1 more source
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Molecular Oncology, EarlyView.Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
A strategies and competitive advantages for study LED firms- The case study for X company
, 2009 [[abstract]]Business strategies and competitive advantages have always been concerned and researched by companies in Taiwan. Good business strategies are important indicators to companies, and competitive advantages are targets of the market and ...
Tsou pei ling
core
PANoptosis in the pathogenesis of myelodysplastic syndromes
Molecular Oncology, EarlyView.PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla +4 more
wiley +1 more source
Spatial biology in cancer epigenetics
Molecular Oncology, EarlyView.Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
ADP‐ribosylation: An emerging regulator of the epigenome
Molecular Oncology, EarlyView.ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho +2 more
wiley +1 more source
Gaining and Losing Competitive Advantage [PDF]
Efficient policies to stimulate the competitiveness of firms require knowledge of future firm-strategies and a proper as-sessment of the location advantages of a country or region.
Christian Bellak
core
A CRITICAL ANALYSIS OF MARKETING STRATEGIES IN ENHANCING THE COMPETITIVE ADVANTAGE OF CAFE PONDOK REZEKI DELI TUA [PDF]
Marketing strategy plays a crucial role in influencing the success and competitiveness of a business. Effective marketing strategies enhance a company's ability to expand its market share and achieve desired profitability.
Ahmad Fadli +4 more
core +1 more source