Results 51 to 60 of about 2,032,664 (124)

The role of C1, C1-inactivator and C4 in modulating immune precipitation

, 1985
To clarify the mechanism of inhibition of immune precipitation by early components of the classical pathway of complement, aggregation of 125I-BSA-rabbit-anti-BSA antibody complexes was performed in the presence of purified C1, C1-inactivator (C1-In) and
Schifferli, J. A., Steiger, G., Schapira, M.   +2 more
core   +1 more source

Complement C1-inhibitor expression in Alzheimer's disease

, 1998
In situ and in vitro studies suggest that activation of locally produced complement factors may act as a mediator between amyloid deposits and neurodegenerative changes seen in Alzheimer's disease (AD).
Hoozemans, J. J., Eikelenboom, P., Hack, C. E., Veerhuis, R, Hoozemans, JJM, Veerhuis, R., de Groot, C. J., De Groot, CJA, Eikelenboom, P, Janssen, I., Hack, CE   +10 more
core   +1 more source

Huntington's disease: An immune perspective [PDF]

, 2011
Copyright © 2011 Annapurna Nayaketal. This article has been made available through the Brunel Open Access Publishing Fund.Huntington's disease (HD) is a progressive neurodegenerative disorder that is caused by abnormal expansion of CAG trinucleotide ...
Kishore, U, Domenico Marco Bonifati, Ansar, R, Verma, SK, Rafia Ansar, Nayak, A, Sunil K. Verma, Annapurna Nayak, Bonifati, DM, Uday Kishore   +9 more
core   +1 more source

Conserved Surface-Exposed K/R-X-K/R Motifs and Net Positive Charge on Poxvirus Complement Control Proteins Serve as Putative Heparin Binding Sites and Contribute to Inhibition of Molecular Interactions with Human Endothelial Cells: a Novel Mechanism for Evasion of Host Defense [PDF]

, 2000
Vaccinia virus complement control protein (VCP) has been shown to possess the ability to inhibit both classical and alternative complement pathway activation.
Shchelkunov, SN, Reynolds, DN, Kotwal, GJ, Justus, DE, Srisatjaluk, R, Loparev, VN, Totmenin, AV, Keeling, KL, Smith, SA, Parkinson, J, Barlow, PN, Mullin, NP   +11 more
core  

Human complement factor H [PDF]

, 1991
Estaller, C., Schwaeble, W., Barbieri, A., Molgg, M., Feifel, E., Koistinen, V., Dierich, Manfred P., Weiss, Elisabeth H.   +7 more
core   +1 more source

A comparative analysis of cowpox virus (CPV WT) and a deletion mutant lacking the gene encoding the inflammation modulatory protein (CPV IMP) [PDF]

, 2007
Includes bibliographical references (leaves 96-114).Cowpox virus has been found to encode the inflammation modulatory protein (IMP) (Miller, C.G., 1997), a homologue vaccinia virus complement control protein (VCP). VCP belongs to regulation of complement
Paulsen, Janis
core   +1 more source

Serum amyloid P aids complement-mediated immunity to Streptococcus pneumoniae [PDF]

, 2007
The physiological functions of the acute phase protein serum amyloid P (SAP) component are not well defined, although they are likely to be important, as no natural state of SAP deficiency has been reported.
Brown, JS, Brown, J.S., Yuste, J., Botto, M., Bottoms, SE, Bottoms, S.E., Yuste, J, Botto, M   +7 more
core  

Pneumococcal histidine triad proteins are regulated by the Zn(2+)-dependent repressor AdcR and inhibit complement deposition through the recruitment of complement factor H

, 2009
The pneumococcal histidine triad (Pht) proteins are a recently recognized family of surface proteins, comprising 4 members: PhtA, PhtB, PhtD, and PhtE. They are being promoted for inclusion in a multicomponent pneumococcal protein vaccine currently under
Sadlon, T., Cook, J., Sadlon, Tania A., Mahdi, Layla K., Ogunniyi, A., Paton, James Cleland, Cook, Jan, Paton, J., Ogunniyi, A D, Gordon, David Llewellyn, Ogunniyi, Abiodun D., Sadlon, Tania, Grabowicz, Marcin, Paton, James C., Grabowicz, M., Gordon, D., Gordon, David L., Mahdi, L.   +17 more
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The complement factsbook /

, 2000
The Complement FactsBook contains entries on all components of the Complement System, including C1q and Lectins, C3 Family, Serine Proteases, Serum Regulators of Complement Activation, Cell Surface Proteins, and Terminal Pathway Proteins.
Morley, Bernard J., Walport, Mark.
core  

Targeting thromboinflammation in COVID-19 - A narrative review of the potential of C1 inhibitor to prevent disease progression. [PDF]

Mol Immunol, 2022
Urwyler P, Moser S, Trendelenburg M, Sendi P, Osthoff M.   +4 more
europepmc   +1 more source