Understanding the first steps of the complement classical pathway: Structural studies on C1-antibody complexes [PDF]
The complement system is a complex network of plasma and membrane-associated proteins, which can produce effective immune responses to infectious micro-organisms. Deficiencies of complement proteins cause diseases like systemic lupus erythematosus (SLE),
Sub Crystal and Structural Chemistry +2 more
core
COVID-19 and hereditary angioedema: Incidence, outcomes, and mechanistic implications. [PDF]
Veronez CL +4 more
europepmc +1 more source
Complement as a vital nexus of the pathobiological connectome for acute respiratory distress syndrome: An emerging therapeutic target. [PDF]
Yang Z +4 more
europepmc +1 more source
Interventions for the long-term prevention of hereditary angioedema attacks. [PDF]
Beard N +5 more
europepmc +1 more source
Complement C2 receptor inhibitor trispanning: a novel human complement inhibitory receptor
The complement system presents a powerful defense against infection and is tightly regulated to prevent damage to self by functionally equivalent soluble and membrane regulators.
Krueger, G. +6 more
core
A novel SERPING1 splice-site variant (c.1029â+â2Tâ>âA) causing hereditary angioedema type I: functional characterization and clinical analysis. [PDF]
Guo W +9 more
europepmc +1 more source
Complement dysregulation is associated with severe COVID-19 illness. [PDF]
Yu J +6 more
europepmc +1 more source
Complement system in cancer: friend or foe of immunotherapy. [PDF]
Shah HK +6 more
europepmc +1 more source
Overexpression of Decay Accelerating Factor Mitigates Fibrotic Responses to Lung Injury. [PDF]
Vittal R +11 more
europepmc +1 more source
Complement response to burn injury: systematic review and meta-analysis of patient and animal studies. [PDF]
Mulder PPG +5 more
europepmc +1 more source

