Results 191 to 200 of about 11,949 (217)

Gingival Crevicular Fluid Proteomic Shift: From Gingivitis to Periodontitis. [PDF]

Int Dent J
Mok JH, Hong JY, Joo M, Yun JH, Park JM.
europepmc   +1 more source

Genetically druggable targets for MAPK-activated colorectal cancer by a two-sample mendelian randomization analysis. [PDF]

Sci Rep
Zhou Y, Ding Y, Xu B, Fei H, Wang Z.
europepmc   +1 more source

Some of the next articles are maybe not open access.

Related searches:

COMPLEMENT ALLOTYPING IN SLE: ASSOCIATION WITH C4A NULL

Australian and New Zealand Journal of Medicine, 1983
Abstract: Immunogenetic factors are important in systemic lupus erythematosus (SLE) and deficiency of a number of complement components is often associated with a lupuslike illness. The complement components Bf, C2 and C4 are encoded within the human major histocompatibility complex (MHC) and are polymorphic.
F T, Christiansen, R L, Dawkins, G, Uko, J, McCluskey, P H, Kay, P J, Zilko   +5 more
openaire   +2 more sources

Complement C4A, C4B and BF haplotypes in Koreans

Tissue Antigens, 1996
Specific alleles at C4A, C4B and BF loci occur in populations and are inherited in complotypes, which are linked with particular HLA haplotypes. Considerable differences in complement allele and complotype frequencies have been observed among various ethnic groups.
K S, Park, M H, Park, T, Juji, K, Tokunaga   +3 more
openaire   +2 more sources

The Phenotype of SLE Associated with Complete Deficiency of Complement Isotype C4A

Journal of Clinical Immunology, 1998
Complete deficiency of the complement C4A isotype is a known genetic risk factor for systemic lupus erythematosus (SLE). The disease phenotype of C4A-deficient patients has never been defined. Among 200 patients with SLE from five centers, 18 (9%) with C4A deficiency were identified.
T R, Welch, C, Brickman, N, Bishof, S, Maringhini, M, Rutkowski, M, Frenzke, N, Kantor   +6 more
openaire   +2 more sources

Complement Activation Products C3a and C4a as Endogenous Antimicrobial Peptides

International Journal of Peptide Research and Therapeutics, 2009
All vertebrate species are constantly challenged by infectious agents and pathogens. In order to fight these infectious agents the human host has developed a sophisticated and powerful immune defense. The complement system, which represents the first defense line of innate immunity is activated immediately, within seconds.
Peter F. Zipfel, Michael Reuter
openaire   +1 more source

Glomerular deposition of the complement C4 isotypes C4A and C4B in glomerulonephritis

Nephrology Dialysis Transplantation, 1996
Complement C4 is a component of the classical complement pathway, which is a major mediator of inflammation in many forms of glomerulonephritis. The two isoforms of C4-C4A and C4B-differ in their physicochemical and functional properties.The glomerular deposition of C4A and C4B was investigated in 39 cases of glomerulonephritis with classical pathway ...
K, Lhotta, A, Schlogl, F, Kronenberg, M, Joannidis, P, Konig   +4 more
openaire   +2 more sources

Complement C4A and C4B Gene Copy Number Study in Alzheimer's Disease Patients

Current Alzheimer Research, 2017
Background/Objectives: Increasing evidence suggests the importance of neuroinflammation in the pathogenesis of Alzheimer’s disease (AD), which is a complex neurodegenerative disorder. Complement activation occurs in the brain of patients with AD and seems to contribute to an important local inflammatory state. Increased expression of the fourth serum
Michele, Zorzetto, Francesca, Datturi, Laura, Divizia, Cristiana, Pistono, Ilaria, Campo, Annalisa, De Silvestri, Mariaclara, Cuccia, Giovanni, Ricevuti   +7 more
openaire   +2 more sources

Complement Components C4A and C4B in Human Lupus

2005
For over half a century low serum complement C4 concentrations have been recognized as a manifestation of systemic lupus erythematosus (SLE). However, the role of C4 in human SLE remains elusive. This is partly because of the unusually complex C4 genetics with frequent variations in gene number, gene size, protein isoforms, and expression levels.
Yan Yang, Erwin K. Chung, Karl Lhotta, Yee Ling Wu, Gloria C. Higgins, Robert M. Rennebohm, Lee A. Hebert, Daniel J. Birmingham, Brad H. Rovin, C. Yung Yu   +9 more
openaire   +1 more source

Human Complement Components C4A and C4B Genetic Diversities: Complex Genotypes and Phenotypes

Current Protocols in Immunology, 2005
AbstractThis unit describes methods that can accurately determine the genotypes and phenotypes of human complement components C4A and C4B. Specifically, they allow investigators to determine how many C4 genes are present in a diploid genome of a human subject and to quantify how many of them encode C4A proteins and how many of them encode C4B proteins.
Erwin K, Chung, Yee Ling, Wu, Yan, Yang, Bi, Zhou, C Yung, Yu   +4 more
openaire   +2 more sources