Different Proteomic Profiles Regarding Antihypertensive Therapy in Preeclampsia Pregnant. [PDF]
Pinto-Souza CC+8 more
europepmc +1 more source
The Role of Complement in the Pathogenesis and Treatment of Myasthenia Gravis. [PDF]
Martinez Salazar A+3 more
europepmc +1 more source
Proteomic analysis of cerebrospinal fluid of amyotrophic lateral sclerosis patients in the presence of autologous bone marrow derived mesenchymal stem cells. [PDF]
Reis ALG+10 more
europepmc +1 more source
Insights into the Antibacterial Properties of Complement Peptides C3a, C4a, and C5a across Vertebrates [PDF]
Abstract Complement peptides C3a, C4a, and C5a are important components of innate immunity in vertebrates. Although they diverged from a common ancestor, only C3a and C4a can act as antibacterial peptides in Homo sapiens, suggesting that C5a has evolved into a purely chemotactic molecule; however, the antibacterial properties of C3a, C4a,
Xu-Jie Zhang+5 more
openaire +4 more sources
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Complement C4A and C4B Gene Copy Number Study in Alzheimer's Disease Patients
Current Alzheimer Research, 2017Background/Objectives: Increasing evidence suggests the importance of neuroinflammation in the pathogenesis of Alzheimer’s disease (AD), which is a complex neurodegenerative disorder. Complement activation occurs in the brain of patients with AD and seems to contribute to an important local inflammatory state. Increased expression of the fourth serum
Annalisa De Silvestri+7 more
openaire +4 more sources
Complement C4A, C4B and BF haplotypes in Koreans
Tissue Antigens, 1996Specific alleles at C4A, C4B and BF loci occur in populations and are inherited in complotypes, which are linked with particular HLA haplotypes. Considerable differences in complement allele and complotype frequencies have been observed among various ethnic groups.
Katsushi Tokunaga+4 more
openaire +4 more sources
RELATIVE CONTRIBUTIONS OF HLA-DQA AND COMPLEMENT C4A LOCI IN DETERMINING SUSCEPTIBILITY TO SYSTEMIC LUPUS ERYTHEMATOSUS [PDF]
The objective of this study was to reassess the role of C4A null alleles in systemic lupus erythematosus (SLE) susceptibility after taking into account the association of DQA*0501 with this disease. The frequency of C4A null alleles in 82 SLE patients and 59 controls was determined using both immunofixation and a TaqI RFLP method.
Davies, E. J.+6 more
openaire +4 more sources
Role of complement C4A in developmental synaptic pruning
Molecular Immunology, 2018Michael C. Carroll+4 more
openaire +3 more sources
COMPLEMENT ALLOTYPING IN SLE: ASSOCIATION WITH C4A NULL
Australian and New Zealand Journal of Medicine, 1983Abstract: Immunogenetic factors are important in systemic lupus erythematosus (SLE) and deficiency of a number of complement components is often associated with a lupuslike illness. The complement components Bf, C2 and C4 are encoded within the human major histocompatibility complex (MHC) and are polymorphic.
R. L. Dawkins+5 more
openaire +3 more sources