Results 221 to 230 of about 697,969 (251)

Complement C4A, C4B and BF haplotypes in Koreans

Tissue Antigens, 1996
Specific alleles at C4A, C4B and BF loci occur in populations and are inherited in complotypes, which are linked with particular HLA haplotypes. Considerable differences in complement allele and complotype frequencies have been observed among various ethnic groups.
Katsushi Tokunaga, Katsushi Tokunaga, Takeo Juji, M.H. Park, K.S. Park   +4 more
openaire   +3 more sources

Decreased Plasma Concentrations of the C4B Complement Protein in Autism

Archives of Pediatrics & Adolescent Medicine, 1994
To determine complement C4 protein concentrations in the plasmas of autistic subjects and their family members.Cross-sectional study.Center for Persons with Disabilities and the Department of Biology, Utah State University, Logan.Forty-two autistic subjects (34 males [81%] and eight females [19%]), 50 of their biologic parents, 21 siblings, and 105 ...
Dennis Odell, Roger A. Burger, Anthony R. Torres, W. Louise Warren, Reed P. Warren   +4 more
openaire   +3 more sources

Gene conversion in salt-losing congenital adrenal hyperplasia with absent complement C4B protein.

Journal of Clinical Endocrinology and Metabolism, 1986
Two of four siblings expressed the salt-losing form of congenital adrenal hyperplasia due to 21-hydroxylase deficiency (CAH) and had identical human lymphocyte antigen (HLA) and complement C4 (fourth component of complement) types (HLA-A3,C4,B35,C4A3 ...
P. Donohoue, C. van Dop, R. Mclean, P. White, N. Jospe,, C. Migeon   +5 more
semanticscholar   +1 more source

Complement components C3b and C4b as potential reliable site-specific diagnostic biomarkers for periodontitis.

Journal of Periodontal Research, 2023
OBJECTIVE This study aimed to investigate the correlation between the expression levels of C3b and C4b in human gingival tissue (GT) and gingival crevicular fluid (GCF) and disease severity in human periodontitis and to determine whether C3b and C4b are ...
Ren-Yeong Huang, Fang-Yi Tseng, Chia-Dan Cheng, T. V. Van Dyke, Cheng-En Sung, Jhong-Jhe You, Pei-Wei Weng, Y. Shieh, Wan-Chien Cheng   +8 more
semanticscholar   +1 more source

Complement C4B null allele status confers risk for systemic lupus erythematosus in a Spanish population.

European journal of immunogenetics, 1998
Genetic susceptibility to systemic lupus erythematosus (SLE) may vary amongst different populations. In UK patients, genes encoded in the HLA class II (DQA*0501/DRB1*0301) and class III [C4A*Q0 and tumour necrosis factor (TNF) polymorphisms] subregions ...
M. Naves, A. Hajeer, L. Teh, E. Davies, J. Ordi‐Ros, P. Perez-Pemen, M. Vilardel-Tarres, W. Thomson, Jane Worthington, W. Ollier   +9 more
semanticscholar   +1 more source

C4b-Binding protein, a regulatory protein of complement

Immunologic Research, 1991
Despite the wealth of structural and functional information on C4BP, it is clear that several aspects of C4BP biology and regulation under normal conditions and in the acute-phase response remain unresolved. Studies to identify which interleukin and cytokines regulate C4BP expression (both α-and β-chains) are underway in our laboratory.
openaire   +3 more sources

Factor I-dependent inactivation of human complement C4b of the classical pathway by C3b/C4b receptor (CR1, CD35) and membrane cofactor protein (MCP, CD46).

Journal of Biochemistry (Tokyo), 1992
Proteolytic inactivation of C4b is a crucial step for regulation of the classical complement pathway. A plasma protease factor I and membrane cofactors, C3b/C4b receptor (CR1) and membrane cofactor protein (MCP), participate in the regulation of cell ...
T. Masaki, M. Matsumoto, I. Nakanishi, R. Yasuda, T. Seya   +4 more
semanticscholar   +1 more source

Glomerular deposition of the complement C4 isotypes C4A and C4B in glomerulonephritis

Nephrology Dialysis Transplantation, 1996
Complement C4 is a component of the classical complement pathway, which is a major mediator of inflammation in many forms of glomerulonephritis. The two isoforms of C4-C4A and C4B-differ in their physicochemical and functional properties.The glomerular deposition of C4A and C4B was investigated in 39 cases of glomerulonephritis with classical pathway ...
Karl Lhotta, M. Joannidis, Florian Kronenberg, Paul König, A. Schlögl   +4 more
openaire   +3 more sources

THE FREQUENCY OF C4B VARIANTS OF COMPLEMENT IN FAMILIAL AND SPORADIC ALZHEIMER DISEASE

Alzheimer Disease & Associated Disorders, 1987
A previous study reported an unexpected increased frequency of the uncommon C4B2 allele of complement in a group of patients with senile dementia of the Alzheimer type. We compared the frequency of various C4B types in 25 patients with familial Alzheimer dementia (AD), 22 patients with sporadic AD, and 360 control individuals.
Thomas D. Bird, Gerard D. Schellenberg, Eric B. Larson, Thomas H. Lampe, Michael Boehnke, Jeanne E. Anderson   +5 more
openaire   +3 more sources

DR-positive T cells in autism: association with decreased plasma levels of the complement C4B protein.

Neuropsychobiology, 1995
Autism is a developmental disorder characterized by severe communication, social and behavioral abnormalities. Over the past several years a fair amount of evidence has accumulated suggesting that some cases of autism may be associated with immune ...
Reed P. Warren, J. Yonk, R. Burger, Dennis Odell, W. Warren   +4 more
semanticscholar   +1 more source