Secretion of soluble complement inhibitors factor H and factor H-like protein (FHL-1) by ovarian tumour cells [PDF]
We observed that the soluble complement regulators factor H and factor H-like protein were abundantly present in ascites samples as well as in primary tumours of patients with ovarian cancer.
Bjørge, L +7 more
core +2 more sources
High Complement Factor I Activity in the Plasma of Children with Autism Spectrum Disorders
Autism Research and Treatment, 2011 Autism spectrum disorders (ASDs) are neurodevelopmental and behavioural syndromes affecting social orientation, behaviour, and communication that can be classified as developmental disorders. ASD is also associated with immune system abnormality.
N. Momeni +7 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.Combining melting curve analysis enhances the multiplexing capability of digital PCR. Here, we developed a 14‐plex assay to simultaneously measure single nucleotide mutations and amplifications of KRAS and GNAS, which are common driver genes in pancreatic cancer precursors. This assay accurately quantified variant allele frequencies in clinical samples
Junko Tanaka +10 more
wiley +1 more source
Exploration of heterogeneity and recurrence signatures in hepatocellular carcinoma
Molecular Oncology, EarlyView.This study leveraged public datasets and integrative bioinformatic analysis to dissect malignant cell heterogeneity between relapsed and primary HCC, focusing on intercellular communication, differentiation status, metabolic activity, and transcriptomic profiles.
Wen‐Jing Wu +15 more
wiley +1 more source
Effect of anti-C5 antibody on recuperation from ischemia/reperfusion-induced acute kidney injury
Renal Failure, 2019 Aim: The complement system is activated in acute kidney injury (AKI). Anti-C5 antibody targets the common terminal portion of the complement cascade that generate the terminal complex C5b-9 and has a renal-protective effect in paroxysmal nocturnal ...
Shani Zilberman-Itskovich +3 more
doaj +1 more source
On complemented non-abelian chief factors of a Lie algebra [PDF]
arXiv, 2015 The number of Frattini chief factors or of chief factors which are complemented by a maximal subalgebra of a finite-dimensional Lie algebra $L$ is the same in every chief series for $L$, by \cite[Theorem 2.3]{[11]}. However, this is not the case for the number of chief factors which are simply complemented in $L$.
arxiv
Molecular Oncology, EarlyView.Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit +19 more
wiley +1 more source
The interaction of C3b bound to pneumococci with factor H (beta 1H globulin), factor I (C3b/C4b inactivator), and properdin factor B of the human complement system. [PDF]
, 1983 E.J. Brown +4 more
openalex +1 more source
Molecular Oncology, EarlyView.This article advocates integrating temporal dynamics into cancer research. Rather than relying on static snapshots, researchers should increasingly consider adopting dynamic methods—such as live imaging, temporal omics, and liquid biopsies—to track how tumors evolve over time.
Gautier Follain +3 more
wiley +1 more source
Factors Affecting Complement Activation by Staphylococcus aureus Cell Walls, Their Components, and Mutants Altered in Teichoic Acid [PDF]
, 1981 Brian J. Wilkinson +2 more
openalex +1 more source