Results 151 to 160 of about 2,740,548 (363)
Molecular Oncology, EarlyView.This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani +14 more
wiley +1 more source
De Novo Atypical Haemolytic Uremic Syndrome after Kidney Transplantation
Case Reports in Nephrology, 2018 De novo thrombotic microangiopathy (TMA) can occur after kidney transplantation. An abnormality of the alternative pathway of complement must be suspected and searched for, even in presence of a secondary cause. We report the case of a 23-year-old female
Arnaud Devresse +4 more
doaj +1 more source
Dentistry and Medical Research, 2019 Background: To evaluate the effect of nonsurgical periodontal therapy on gingival crevicular fluid (GCF) and serum levels of complement C3 and factor B and their correlation with Porphyromonas gingivalis levels in chronic periodontitis (CP) individuals ...
Srirangarajan Sridharan +1 more
doaj +1 more source
Investigations of hadron structure on the lattice [PDF]
PoS LATTICE2008:007,2008, 2008 Lattice simulations of hadronic structure are now reaching a level where they are able to not only complement, but also provide guidance to current and forthcoming experimental programmes at, e.g. Jefferson Lab, COMPASS/CERN and FAIR/GSI. In this talk I review the progress that has been made in this exciting area in the past year and discuss the ...
arxiv
Molecular modelling of the domain structure of factor I of human complement by X-ray and neutron solution scattering [PDF]
, 1993 Stephen J. Perkins +2 more
openalex +1 more source
Molecular Oncology, EarlyView.B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez +17 more
wiley +1 more source
Ubiquitination of transcription factors in cancer: unveiling therapeutic potential
Molecular Oncology, EarlyView.In cancer, dysregulated ubiquitination of transcription factors contributes to the uncontrolled growth and survival characteristics of tumors. Tumor suppressors are degraded by aberrant ubiquitination, or oncogenic transcription factors gain stability through ubiquitination, thereby promoting tumorigenesis.
Dongha Kim, Hye Jin Nam, Sung Hee Baek
wiley +1 more source
Lattice Complements and the Subadditivity of Syzygies of Simplicial Forests [PDF]
arXiv, 2016 We prove the subadditivity property for the maximal degrees of the syzygies of facet ideals simplicial forests. For such an ideal $I$, if the $i$-th Betti number is nonzero and $i=a+b$, we show that there are monomials in the lcm lattice of $I$ that are complements in part of the lattice, each supporting a nonvanishing $a$-th and $b$-th Betti numbers ...
arxiv
Genomic Organization of the Serine Protease Light Chain of Mouse Complement Factor I Gene [PDF]
, 2000 Ning Jiang, Hector Molina
openalex +1 more source
Role of the I416L Variant of Complement Factor I in Thrombotic Microangiopathy Among Patients of African Ancestry. [PDF]
Kidney Int Rep, 2023 Nobile G +6 more
europepmc +1 more source