Results 31 to 40 of about 1,866,008 (218)
BMJ Open Ophthalmology, 2020 Objective Systemic activation of the complement system in intermediate age-related macular degeneration (AMD) is understudied. Moreover, links between the presence of reticular pseudodrusen (RPD) and systemic complement dysregulation have not been ...
Anne M Lynch +8 more
doaj +1 more source
Factorization fits and the unitarity triangle in charmless two-body B decays [PDF]
Phys.Rev.D68:113005,2003, 2003 We present fits to charmless hadronic B decay data from the BaBar, Belle and Cleo experiments using two theoretical models: (i) the QCD factorization model of Beneke et al. and (ii) QCD factorization complemented with the so-called charming penguins of Ciuchini et al.
arxiv +1 more source
Inhibition of c3 convertase activity by hepatitis C virus as an additional lesion in the regulation of complement components. [PDF]
PLoS ONE, 2014 We have previously reported that in vitro HCV infection of cells of hepatocyte origin attenuates complement system at multiple steps, and attenuation also occurs in chronically HCV infected liver, irrespective of the disease stage. However, none of these
Hangeun Kim +3 more
doaj +1 more source
Effect of Heme Oxygenase-1 Depletion on Complement Regulatory Proteins Expression in the Rat
Antioxidants, 2022 Heme oxygenase has been implicated in the regulation of various immune responses including complement activation. Using a transgenic rat model of HO-1 depletion, the present study assessed the effect of HO-1 absence on the expression of complement ...
Maria G. Detsika +4 more
doaj +1 more source
Some open questions on arithmetic Zariski pairs [PDF]
Singularities in geometry, topology, foliations and dynamics,
31-54, Trends Math., Birkh\"auser/Springer, Cham, 2017, 2015 In this paper, complement-equivalent arithmetic Zariski pairs will be exhibited answering in the negative a question by Eyral-Oka on these curves and their groups. A complement-equivalent arithmetic Zariski pair is a pair of complex projective plane curves having Galois-conjugate equations in some number field whose complements are homeomorphic, but ...
arxiv +1 more source
Antibiotics, 2022 Candidiasis is common in diabetic patients. Complement evasion is facilitated by binding complement factor H (FH). Since the expression of high-affinity glucose transporter 1 (Hgt1), a FH-binding molecule, is glucose-dependent, we aimed to study its ...
Verena Harpf +10 more
doaj +1 more source
Genetic Risk in Families with Age-Related Macular Degeneration
Ophthalmology Science, 2021 Purpose: To determine the contribution of common and rare genetic risk variants in families with age-related macular degeneration (AMD). Design: Case-control study.
Anita de Breuk, MD +6 more
doaj
Translational Psychiatry, 2023 Immunological/inflammatory factors are implicated in the development of psychosis. Complement is a key driver of inflammation; however, it remains unknown which factor is better at predicting the onset of psychosis.
TianHong Zhang +12 more
doaj +1 more source
Hypoglycemia-induced changes in complement pathways in type 2 diabetes
Atherosclerosis Plus, 2021 Background and aims: An association between hypoglycaemia and adverse cardiovascular events has been suggested from longitudinal and retrospective cohort studies. The complement pathway proteins in hypoglycemia are not well studied. Here, we hypothesized
Abu Saleh Md Moin +6 more
doaj
Antibodies, 2013 The CD20 mAbs, rituximab (RTX) and ofatumumab (OFA), have been used with success in the clinic in the treatment of B cell malignancies. These mAbs can eliminate B cells only by utilizing the body’s immune effector mechanisms, and there is considerable ...
Margaret A. Lindorfer +2 more
doaj +1 more source