Results 41 to 50 of about 1,866,008 (218)
Acquisition of complement inhibitor serine protease factor I and its cofactors C4b-binding protein and factor H by Prevotella intermedia. [PDF]
PLoS ONE, 2012 Infection with the Gram-negative pathogen Prevotella intermedia gives rise to periodontitis and a growing number of studies implies an association of P. intermedia with rheumatoid arthritis.
Sven Malm +5 more
doaj +1 more source
In Memory of Sir Peter J. Lachmann, 1931–2020—Bees, Tickover, Factor I and Complement
Viruses, 2021 We were all very sorry to hear that our highly esteemed colleague and one of the true pioneers of complement research, Professor, Sir Peter J [...]
Seppo Meri
doaj +1 more source
FEBS Letters, EarlyView.Low‐density lipoprotein receptor‐related protein 6 (LRP6) is a key receptor for the Wnt antagonist Dickkopf1 (DKK1). DKK1 protein expression is induced in a bleomycin (BLM)‐induced lung injury model. We show that DKK1 induces proinflammatory and profibrotic genes in lung fibroblasts.
Eun‐Ah Sung +6 more
wiley +1 more source
Unraveling Mycobacterium tuberculosis acid resistance and pH homeostasis mechanisms
FEBS Letters, EarlyView.Mycobacterium tuberculosis exhibits a remarkable resilience to acid stress. In this Review, we discuss some of the molecular mechanisms and metabolic pathways used by the tubercle bacilli to adapt and resist host‐mediated acid stress. Mycobacterium tuberculosis (Mtb) is a successful pathogen that has developed a variety of strategies to survive and ...
Janïs Laudouze +3 more
wiley +1 more source
Self-Similar Factor Approximants [PDF]
Physical Review E 67 (2), art. 026109, DOI: 10.1103 (2003), 2002 The problem of reconstructing functions from their asymptotic expansions in powers of a small variable is addressed by deriving a novel type of approximants. The derivation is based on the self-similar approximation theory, which presents the passage from one approximant to another as the motion realized by a dynamical system with the property of group
arxiv +1 more source
The power of microRNA regulation—insights into immunity and metabolism
FEBS Letters, EarlyView.MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto +2 more
wiley +1 more source
Primary extranodal diffuse large B‐cell lymphoma: Molecular features, treatment, and prognosis
Aging and Cancer, Volume 3, Issue 3-4, Page 133-146, September-December 2022., 2022 One‐third of DLBCL arises from extranodal organs and is challenging to manage. Molecular features are critical to elucidate the differences in clinical features, predict the disease prognosis, and improve effective targeted therapeutic strategies. Abstract Diffuse large B‐cell lymphoma (DLBCL) is the most common subtype of non‐Hodgkin's lymphoma and ...
Si‐Yuan Chen +3 more
wiley +1 more source
FEBS Letters, EarlyView.In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley +1 more source
A Theory of I/O-Efficient Sparse Neural Network Inference [PDF]
arXiv, 2023 As the accuracy of machine learning models increases at a fast rate, so does their demand for energy and compute resources. On a low level, the major part of these resources is consumed by data movement between different memory units. Modern hardware architectures contain a form of fast memory (e.g., cache, registers), which is small, and a slow memory
arxiv
Resolvable Mendelsohn designs and finite Frobenius groups [PDF]
Bulletin of the Australian Mathematical Society 98 (2018) 1-13, 2013 We prove the existence and give constructions of a $(p(k)-1)$-fold perfect resolvable $(v, k, 1)$-Mendelsohn design for any integers $v > k \ge 2$ with $v \equiv 1 \mod k$ such that there exists a finite Frobenius group whose kernel $K$ has order $v$ and whose complement contains an element $\phi$ of order $k$, where $p(k)$ is the least prime factor of
arxiv +1 more source