Results 61 to 70 of about 2,390,880 (343)

Novel factors of Anopheles gambiae haemocyte immune response to Plasmodium berghei infection [PDF]

, 2016
Background Insect haemocytes mediate cellular immune responses (e.g., phagocytosis) and contribute to the synthesis of humoral immune factors. In previous work, a genome-wide molecular characterization of Anopheles gambiae circulating haemocytes was ...
Christophides, GK, Lombardo, F
core   +3 more sources

Genetic Risk in Families with Age-Related Macular Degeneration

Ophthalmology Science, 2021
Purpose: To determine the contribution of common and rare genetic risk variants in families with age-related macular degeneration (AMD). Design: Case-control study.
Anita de Breuk, MD, Yara T.E. Lechanteur, MD, PhD, Thomas J. Heesterbeek, MD, PhD, Sascha Fauser, MD, PhD, Caroline C.W. Klaver, MD, PhD, Carel B. Hoyng, MD, PhD, Anneke I. den Hollander, PhD   +6 more
doaj  

Serum complement proteins rather than inflammatory factors is effective in predicting psychosis in individuals at clinical high risk

Translational Psychiatry, 2023
Immunological/inflammatory factors are implicated in the development of psychosis. Complement is a key driver of inflammation; however, it remains unknown which factor is better at predicting the onset of psychosis.
TianHong Zhang, JiaHui Zeng, JiaYi Ye, YuQing Gao, YeGang Hu, LiHua Xu, YanYan Wei, XiaoChen Tang, HaiChun Liu, Tao Chen, ChunBo Li, ChunLing Wan, JiJun Wang   +12 more
doaj   +1 more source

Effect of Heme Oxygenase-1 Depletion on Complement Regulatory Proteins Expression in the Rat

Antioxidants, 2022
Heme oxygenase has been implicated in the regulation of various immune responses including complement activation. Using a transgenic rat model of HO-1 depletion, the present study assessed the effect of HO-1 absence on the expression of complement ...
Maria G. Detsika, Eirini Theochari, Kostas Palamaris, Harikleia Gakiopoulou, Elias A. Lianos   +4 more
doaj   +1 more source

Mapping of the human complement factor I gene to 4q25

Genomics, 1989
A detailed genetic and physical map of human complement factor I (IF) using somatic cell hybrids, in situ hybridization, and genetic linkage is reported. The gene has been localized to band 4q25. The order GC-INP10-ADH3-EGF-IF-IL2-MNS is proposed for genes on 4q on the basis of genetic and physical mapping techniques. A BclI polymorphism found with the
Shiang, R, Murray, J C, Morton, C C, Buetow, K H, Wasmuth, J J, Olney, A H, Sanger, W G, Goldberger, G   +7 more
openaire   +4 more sources

Induction of chromosome shattering by ultraviolet light and caffeine: The influence of different distributions of photolesions [PDF]

, 1986
Cells of synchonized and of asynchronously growing cultures of a V79 Chinese hamster line were microirradiated with a low poweer laser-UV-microbeam of wavelength 257 nm.
Barranco, Brenner, Cornelis, Cremer, Cremer, Cremer, Cremer, Cremer, Cremer, Cremer, Cremer, Cremer, Cremer, Cremer, Cremer, Cremer, Cremer, Cremer, González-Fernández, Hens, Kihlman, Kihlman, Kihlman, Kihlman, Lau, Lehmann, Moreno, Nilsson, Painter, Painter, Raith, Rappold, Roberts, Schardin, Sedgwick, Setlow, Stack, Steward, Tatsumi, Tobey, Tomulin, Zorn, Zorn   +42 more
core   +1 more source

Deficient IFN signaling by myeloid cells leads to MAVS-dependent virus-induced sepsis [PDF]

, 2014
The type I interferon (IFN) signaling response limits infection of many RNA and DNA viruses. To define key cell types that require type I IFN signaling to orchestrate immunity against West Nile virus (WNV), we infected mice with conditional deletions of ...
Aggarwal, Shilpa, Atkinson, John P, Diamond, Michael S, Gale, Michael, Jr., Gorman, Matthew, Kim, Kristin Y, Pinto, Amelia K, Ramos, Hilario J, Shrestha, Bimmi, Suthar, Mehul S, Wu, Xiaobo   +10 more
core   +4 more sources

Hypoglycemia-induced changes in complement pathways in type 2 diabetes

Atherosclerosis Plus, 2021
Background and aims: An association between hypoglycaemia and adverse cardiovascular events has been suggested from longitudinal and retrospective cohort studies. The complement pathway proteins in hypoglycemia are not well studied. Here, we hypothesized
Abu Saleh Md Moin, Manjula Nandakumar, Ilhame Diboun, Ahmed Al-Qaissi, Thozhukat Sathyapalan, Stephen L. Atkin, Alexandra E. Butler   +6 more
doaj  

CD20 mAb-Mediated Complement Dependent Cytotoxicity of Tumor Cells is Enhanced by Blocking the Action of Factor I

Antibodies, 2013
The CD20 mAbs, rituximab (RTX) and ofatumumab (OFA), have been used with success in the clinic in the treatment of B cell malignancies. These mAbs can eliminate B cells only by utilizing the body’s immune effector mechanisms, and there is considerable ...
Margaret A. Lindorfer, Paul V. Beum, Ronald P. Taylor   +2 more
doaj   +1 more source

Complement and Coagulation Cascade Activation Regulates the Early Inflammatory Mechanism of Resistance of Suckling Lambs Against Haemonchus contortus

Pathogens
Haemonchus contortus is a highly pathogenic blood-sucking nematode from the abomasum of small ruminants. To develop effective control strategies, it is essential to understand the initial mechanisms involved in host resistance to this parasite.
José Gabriel G. Lins, Alessandro F. T. Amarante   +1 more
doaj   +1 more source