Results 71 to 80 of about 2,390,880 (343)

Acquisition of complement inhibitor serine protease factor I and its cofactors C4b-binding protein and factor H by Prevotella intermedia. [PDF]

open access: yesPLoS ONE, 2012
Infection with the Gram-negative pathogen Prevotella intermedia gives rise to periodontitis and a growing number of studies implies an association of P. intermedia with rheumatoid arthritis.
Sven Malm   +5 more
doaj   +1 more source

Hereditary complement factor I deficiency [PDF]

open access: yes, 2017
Summary We describe four cases (from three families) of hereditary factor I deficiency, bringing the total number of cases now reported to 23. In one family there are two affected siblings: one has suffered recurrent pyogenic infections; the other is ...
ATHANASSIOU, P.   +7 more
core  

Interactions between human complement components factor H, factor I and C3b [PDF]

open access: yesBiochemical Journal, 1997
Using a microtitre plate assay, direct binding between complement factors I and H was demonstrated, and ligand blotting indicated that factor H interacts with the heavy chain of factor I. Similarly, direct C3(NH3)–factor I and C3(NH3)–factor H binding was characterized [where C3(NH3) is a form of C3 that is cleaved by factor I in the presence of factor
Candida J. Soames, Robert B. Sim
openaire   +3 more sources

occumb: An R package for site occupancy modeling of eDNA metabarcoding data

open access: yesPopulation Ecology, EarlyView.
This study introduces a new R package, occumb, for the convenient application of site occupancy modeling using environmental DNA (eDNA) metabarcoding data. We outline a data analysis workflow, including data setup, model fitting, model assessment, and comparison of potential study settings based on model predictions, all of which can be performed using
Keiichi Fukaya, Yuta Hasebe
wiley   +1 more source

COSMIC LITHIUM: GOING UP OR COMING DOWN ? [PDF]

open access: yes, 1995
Observations of interstellar lithium provide a valuable complement to studies of lithium in Pop I and Pop II stars. Large corrections for unseen LiII and for non-gas phase lithium have provided obstacles to using interstellar data for abundance ...
STEIGMAN, GARY
core   +3 more sources

The immunological interface: dendritic cells as key regulators in metabolic dysfunction‐associated steatotic liver disease

open access: yesFEBS Letters, EarlyView.
Metabolic dysfunction‐associated steatotic liver disease (MASLD) affects nearly one‐third of the global population and poses a significant risk of progression to cirrhosis or liver cancer. Here, we discuss the roles of hepatic dendritic cell subtypes in MASLD, highlighting their distinct contributions to disease initiation and progression, and their ...
Camilla Klaimi   +3 more
wiley   +1 more source

The cytoskeletal control of B cell receptor and integrin signaling in normal B cells and chronic lymphocytic leukemia

open access: yesFEBS Letters, EarlyView.
In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley   +1 more source

In Memory of Sir Peter J. Lachmann, 1931–2020—Bees, Tickover, Factor I and Complement

open access: yesViruses, 2021
We were all very sorry to hear that our highly esteemed colleague and one of the true pioneers of complement research, Professor, Sir Peter J [...]
Seppo Meri
doaj   +1 more source

Complement Biomarkers as Predictors of Disease Progression in Alzheimer's Disease [PDF]

open access: yes, 2016
There is a critical unmet need for reliable markers of disease and disease course in mild cognitive impairment (MCI) and early Alzheimer's disease (AD).
Aiyaz, M   +9 more
core   +4 more sources

Complement resistance is a virulence factor ofBranhamella (Moraxella) catarrhalis [PDF]

open access: yesFEMS Immunology & Medical Microbiology, 1995
The purpose of this study was to investigate complement resistance in Branhamella (Moraxella) catarrhalis isolated from healthy schoolchildren or sputum-producing adult patients. Two techniques were used: a serum bactericidal assay as the gold standard and an easier 'culture and spot' test.
Cees M. Verduin   +5 more
openaire   +3 more sources

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