Results 101 to 110 of about 484,151 (372)

Extracting the barbs from complement assays: Identification and optimisation of a safe substitute for traditional buffers [PDF]

open access: yes, 2018
Complement assays have for many years utilised buffers based on barbitone (veronal) despite the well-recognised toxicity of this agent and the tight regulations on its use in most countries.
Harris, Claire L.   +2 more
core   +2 more sources

An extension to the OVH concept for knowledge‐based dose volume histogram prediction in lung tumor volumetric‐modulated arc therapy

open access: yesJournal of Applied Clinical Medical Physics, EarlyView.
Abstract Purpose Volumetric‐modulated arc therapy (VMAT) treatment planning allows a compromise between a sufficient coverage of the planning target volume (PTV) and a simultaneous sparing of organs‐at‐risk (OARs). Particularly in the case of lung tumors, deciding whether it is possible or worth spending more time on further improvements of a treatment
Johann Brand   +4 more
wiley   +1 more source

Learning a Saliency Evaluation Metric Using Crowdsourced Perceptual Judgments [PDF]

open access: yesarXiv, 2018
In the area of human fixation prediction, dozens of computational saliency models are proposed to reveal certain saliency characteristics under different assumptions and definitions. As a result, saliency model benchmarking often requires several evaluation metrics to simultaneously assess saliency models from multiple perspectives.
arxiv  

Brucellosis and chlamydiosis seroprevalence in goats at livestock–wildlife interface areas of Zimbabwe [PDF]

open access: yes, 2019
In Zimbabwe, there have been no chlamydiosis and limited brucellosis studies in goats. This study was conducted to determine the seroprevalence and risk factors of the two diseases in goats at three different livestock–wildlife interface areas: porous ...
Bhandi, Solomon   +8 more
core   +1 more source

Epigenome‐wide association study, meta‐analysis, and multiscore profiling of whole blood in Parkinson's disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
Abstract Objectives An increasing body of evidence indicates altered DNA methylation in Parkinson's disease, yet the reproducibility and utility of such methylation changes are largely unexplored. We aimed to further elucidate the role of dysregulated DNA methylation in Parkinson's disease and to evaluate the biomarker potential of methylation‐based ...
Ingeborg Haugesag Lie   +4 more
wiley   +1 more source

Evidence of blood–brain barrier dysfunction and CSF immunoglobulin synthesis in Down Syndrome Regression Disorder

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
Abstract Objectives This study sought to evaluate proteomic, metabolomic, and immune signatures in the cerebrospinal fluid of individuals with Down Syndrome Regression Disorder (DSRD). Methods A prospective case–control study comparing proteomic, metabolomic, and immune profiles in individuals with DSRD was performed.
Jonathan D. Santoro   +12 more
wiley   +1 more source

A Complement Fixation Test for Herpes Simplex Infections

open access: yesJournal of Clinical Pathology, 1950
The serological diagnosis of virus infections depends for the most part on neutralization and complement fixation tests. Both of these have been described in the case of herpes simplex infections, but the neutralization test is used almost exclusively at
J. Dudgeon
semanticscholar   +1 more source

Cerebral Amyloid Angiopathy Is Associated With Higher R2 Relaxation Rate: An MRI and Pathology Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cerebral amyloid angiopathy (CAA) involves β‐amyloid deposition in the walls of cortical and leptomeningeal small vessels. Transverse relaxation rate (R2) is a major source of contrast in MRI. This study tested the hypothesis that CAA is associated with R2, extracted the spatial pattern of CAA‐related R2 abnormalities, and evaluated ...
Md Tahmid Yasar   +6 more
wiley   +1 more source

Human FcRn can mediate the transport across intestinal mucosal barrier and prolong the half-life of rabbit IgG in vivo

open access: yesBrazilian Archives of Biology and Technology, 2015
FcRn (neonatal Fc receptor) plays an important role in IgG transportation, antigen presentation and signal transmission. In this study, the complement fixation test and flow cytometry test were performed to verify whether the heterologous antibody could ...
Guangchang Pang   +4 more
doaj   +1 more source

Contour Completion Around a Fixation Point [PDF]

open access: yesarXiv, 2012
The paper presents two edge grouping algorithms for finding a closed contour starting from a particular edge point and enclosing a fixation point. Both algorithms search a shortest simple cycle in \textit{an angularly ordered graph} derived from an edge image where a vertex is an end point of a contour fragment and an undirected arc is drawn between a ...
arxiv  

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