Results 61 to 70 of about 135,513 (316)

Estudos sobre a reação de Guerreiro-Machado. Efeitos da inativação do soro chagásico na fixação do complemento com antígeno de Trypanosoma cruzi Study on Guerreiro-Machado reaction. Inactivation effect of Chagas's serum in complement fixation with Trypanosoma cruzi antigen

Memorias do Instituto Oswaldo Cruz, 1981
O aquecimento de soros chagásicos a 56 grausC por 30 minutos, não só inativa o complemento, como altera a mobilidade iônica das proteínas séricas. Com a inativação, os títulos dos soros por fixação de complemento decrescem sendo a queda do poder fixador ...
José Oliveira de Almeida, Therezinha Aparecida Cunha   +1 more
doaj   +1 more source

Seroprevalence of brucellosis in communal and smallholder cattle farming in North West Province, South Africa

Onderstepoort Journal of Veterinary Research, 2023
Brucellosis is an important bacterial zoonosis responsible for considerable economic losses in livestock and health-related burden worldwide. The objective of this study was to determine the seroprevalence of brucellosis in communal and smallholder ...
Bontsi Marumo, Tiny M. Hlokwe, Prudence N. Kayoka-Kabongo   +2 more
doaj   +1 more source

Exploration of heterogeneity and recurrence signatures in hepatocellular carcinoma

Molecular Oncology, EarlyView.
This study leveraged public datasets and integrative bioinformatic analysis to dissect malignant cell heterogeneity between relapsed and primary HCC, focusing on intercellular communication, differentiation status, metabolic activity, and transcriptomic profiles.
Wen‐Jing Wu, Jianchao Wang, Fuqing Chen, Xuefeng Wang, Bin Lan, Ruyi Fu, Hong Wen, Fangfang Chen, Wei Hong, Tian‐Yu Tang, Ying He, Gang Chen, Jianyin Zhou, Hai‐Long Piao, Di Chen, Shu‐Yong Lin   +15 more
wiley   +1 more source

The Characterization of Complement Fixing Circulating Anti-Body by the Jird (Meriones Unguiculatus) in Response to Infection with Brugia Pahangi over an Extended Period of Time [PDF]

, 1981
Male outbred jirds (Merione unguiculatus) were inoculated with doses of 100 or 200 infective Brugia pahangi larvae (1_3’s), and tested for complement fixing circulating antibody.
Sorge, Kevin F.
core   +3 more sources

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

Molecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani, Gilgi Friedlander, Gili Perry, Nora Balint‐Lahat, Shlomit Gilad, Dana Morzaev‐Sulzbach, Anjana Shenoy, Noa Bossel Ben‐Moshe, Anya Pavlovsky, Rinat Bernstein‐Molho, Eytan Domany, Iris Barshack, Tamar Geiger, Bella Kaufman, Einav Nili Gal‐Yam   +14 more
wiley   +1 more source

Validation de terrain d'un test ELISA de compétition pour la détection de la péripneumonie contagieuse des bovins au Botswana [PDF]

, 1998
Le test ELISA de compétition, récemment décrit pour détecter la présence de la péripneumonie, a été utilisé au Laboratoire national vétérinaire du Botswana à Gaborone. L'échantillonnage de sérums a compris un nombre significatif de sérums récoltés durant
Amanfu, William, Benkirane, A., Geiger, R., Masupu, K.V., Sediadie, S., Thiaucourt, François   +5 more
core  

Ubiquitination of transcription factors in cancer: unveiling therapeutic potential

Molecular Oncology, EarlyView.
In cancer, dysregulated ubiquitination of transcription factors contributes to the uncontrolled growth and survival characteristics of tumors. Tumor suppressors are degraded by aberrant ubiquitination, or oncogenic transcription factors gain stability through ubiquitination, thereby promoting tumorigenesis.
Dongha Kim, Hye Jin Nam, Sung Hee Baek
wiley   +1 more source

Immunological and Immunohistochemical Methods Used to Study Chromatin Neoantigens of Novikoff Hepatoma [PDF]

, 1980
The micro-complement fixation test was used to assay the potency and specificity of rabbit antisera to chromosomal antigens from Novikoff hepatoma and normal rat liver. The complement fixation titration patterns suggest the presence of only a few species
Binette, Steven, O'Connor, Timothy
core   +1 more source

Oropouche Virus Isolation, Southeast Brazil

Emerging Infectious Diseases, 2005
An Oropouche virus strain was isolated from a novel host (Callithrix sp.) in Arinos, Minas Gerais State, southeastern Brazil. The virus was identified by complement fixation test and confirmed by reverse transcription–polymerase chain reaction ...
Márcio Roberto Teixeira Nunes, Lívia Carício Martins, Sueli Guerreiro Rodrigues, Jannifer Oliveira Chiang, Raimunda do Socorro da Silva Azevedo, Amelia P.A. Travassos da Rosa, Pedro Fernando da Costa Vasconcelos   +6 more
doaj   +1 more source

Loss of proton‐sensing GPR4 reduces tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
G protein‐coupled receptor 4 (GPR4) is a pH‐sensing receptor activated by acidic pH. GPR4 expression is increased in patients with inflammatory bowel disease who are at high risk of developing colorectal cancer. In mouse models, loss of GPR4 attenuated tumor progression. This correlated with increased IL2 and natural killer cell activity.
Leonie Perren, Moana Busch, Pedro A. Ruiz, Ermanno Malagola, Valeria Baumeler, Federica Foti, Adelina Gross, Tobias Grütter, Hendrik Edel, Cordelia Schuler, Kristina Handler, Glenn De Lange, Isabelle C. Arnold, Cheryl de Vallière, Klaus Seuwen, Martin Hausmann, Gerhard Rogler   +16 more
wiley   +1 more source