Results 71 to 80 of about 135,513 (316)

Serological screening of Coxiella burnetii (Q fever) and Brucella spp. in sheep flocks in the northern prefectures of Japan in 2007 [PDF]

Veterinaria Italiana, 2012
Ovine sera collected from the northern Prefectures of Hokkaido, Iwate and Aomori in Japan, were examined for the presence of antibodies against Coxiella burnetii (Q fever) using the complement fixation test and, against Brucella spp., using both the ...
Ryô Harasawa, Serena Robetto, Riccardo Orusa, Barbara Bonfini, Takeshi Osawa, Massimo Giangaspero   +5 more
doaj  

Clinical investigation and management of Brucella suis seropositive dogs: A longitudinal case series

Journal of Veterinary Internal Medicine, 2023
Background Brucellosis in dogs caused by Brucella suis is an emerging zoonotic disease. Objectives To document clinical characteristics, serology, microbiology, and clinical response to treatment in B. suis‐seropositive dogs.
Catherine C. Kneipp, Ania T. Deutscher, Ronald Coilparampil, Anne Marie Rose, Jennifer Robson, Richard Malik, Mark A. Stevenson, Anke K. Wiethoelter, Siobhan M. Mor   +8 more
doaj   +1 more source

Therapeutic applications of a novel humanized monoclonal antibody targeting chemokine receptor CCR9 in pancreatic cancer

Molecular Oncology, EarlyView.
C–C chemokine receptor type 9 (CCR9) is an immune checkpoint in pancreatic ductal adenocarcinoma (PDAC). Novel anti‐CCR9 antibody SRB2 was evaluated in combination with cytotoxic chemotherapy in PDAC cells, patient‐derived organoids, patient‐derived xenografts, and humanized mouse models.
Hannah G. McDonald, Anna M. Reagan, Charles J. Bailey, Mei Gao, Muqiang Gao, Angelica L. Solomon, Michael J. Cavnar, Prakash K. Pandalai, Mautin T. Barry‐Hundeyin, Megan M. Harper, Justin A. Rueckert, Ángela Turrero, Araceli Tobio, Anxo Vidal, Daniel Roca‐Lema, Elia Álvarez‐Coiradas, Pablo Garrido, Laureano Simón, Joseph Kim   +18 more
wiley   +1 more source

Coccidioidomycosis Complement Fixation Titer Trends in the Age of Antifungals. [PDF]

, 2018
Coccidioidomycosis is associated with a broad spectrum of illness severity, ranging from asymptomatic or self-limited pulmonary infection to life-threatening manifestations of disseminated disease.
Bays, Derek, Dinh, Bao-Tran N, McHardy, Ian H, Pappagianis, Demosthenes, Stewart, Ethan, Thompson, George R, Waldman, Sarah   +6 more
core  

Hotting-up the complement-fixation test [PDF]

Journal of Hygiene, 1983
SUMMARYA detailed investigation into the effect of modifying the incubation temperature of the complement-fixation (CF) test is described. For varicella-zoster virus cytomegalovirus and rubella virus, increasing the incubation temperature progressively increased the sensitivity of the CF test to reach a maximum at 15°C, at which temperature the ...
P. D. Griffiths, C. J. Ronalds, A. E. Hardiman   +2 more
openaire   +3 more sources

BMP antagonist CHRDL2 enhances the cancer stem‐cell phenotype and increases chemotherapy resistance in colorectal cancer

Molecular Oncology, EarlyView.
Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley   +1 more source

C1q-targeted inhibition of the classical complement pathway prevents injury in a novel mouse model of acute motor axonal neuropathy [PDF]

, 2016
Introduction Guillain-Barré syndrome (GBS) is an autoimmune disease that results in acute paralysis through inflammatory attack on peripheral nerves, and currently has limited, non-specific treatment options.
Barrie, Jennifer A., Cunningham, Madeleine E., Fewou, Simon N., Furukawa, Koichi, McGonigal, Rhona, Sankaranarayanan, Sethu, Willison, Hugh J., Yao, Denggao, Yednock, Ted A.   +8 more
core   +2 more sources

Acute phase biomarkers, oxidants, antioxidants, and trace minerals of mobile sheep flocks naturally infected with brucellosis

Bulgarian Journal of Veterinary Medicine, 2021
This study assayed the acute phase responses of sheep seropositive to Brucella. Sera collected from ewes (n=160) were subjected to serological tests of Brucella, Rose Bengal plate agglutination test (RBPAT), buffer acidified plate agglutination test ...
N. A. Shalby, A. M. Abo El-Maaty, A. H. Ali , M. Elgioushy   +3 more
doaj   +1 more source

Simultaneous inhibition of TRIM24 and TRIM28 sensitises prostate cancer cells to antiandrogen therapy, decreasing VEGF signalling and angiogenesis

Molecular Oncology, EarlyView.
TRIM24 and TRIM28 are androgen receptor (AR) coregulators which exhibit increased expression with cancer progression. Both TRIM24 and TRIM28 combine to influence the response of castrate‐resistant prostate cancer (CRPC) cells to AR inhibitors by mediating AR signalling, regulation of MYC and upregulating VEGF to promote angiogenesis. Castrate‐resistant
Damien A. Leach, Nilesh Chatterjee, Kellie Spahr, Gilberto Serrano de Almeida, Anabel Varela‐Carver, Taimur T. Shah, Mathias Winkler, Hashim U. Ahmed, Charlotte L. Bevan   +8 more
wiley   +1 more source

Categorisation of activities of daily living of lower limb amputees during short-term use of a portable kinetic recording system: a preliminary study [PDF]

, 2011
The purpose of this preliminary study was to determine the relevance of the categorisation of the load regime data to assess the functional output and usage of the prosthesis of lower limb amputees.
Frossard , Laurent, Pearcy , Mark, Stevenson , Nathan, Sullivan , John, Uden , Maggie   +4 more
core   +2 more sources