Results 81 to 90 of about 484,151 (372)
Germline variants in CDKN2A wild‐type melanoma prone families
Molecular Oncology, EarlyView.Among melanoma‐prone families, wild‐type for CDKN2A and CDK4, some have pathogenic variants in genes not usually linked to melanoma. Furthermore, rare XP‐related variants and variants in MC1R are enriched in such families. Germline pathogenic variants in CDKN2A are well established as an underlying cause of familial malignant melanoma. While pathogenic
Gjertrud T. Iversen +5 more
wiley +1 more source
Measuring and simulating the biophysical basis of the acoustic contrast factor of biological cells [PDF]
arXiv, 2023 The acoustic contrast factor (ACF) is calculated from the relative density and compressibility differences between a fluid and an object in the fluid. To name but one application, this acoustic contrast can be exploited using acoustophoretic systems to isolate cancer cells from a liquid biopsy, such as a blood sample.
arxiv
Complement fixation with horsesickness viruses [PDF]
, 1956 Fixation of complement bas been obtained using antigens prepared from suckling mouse brains and antisera from hyperimmune guinea-pigs. With horsesickness viruses the complement fixation test is less type specific than the neutralization test and no ...
McIntosh, B.M.
core
Epidemiology and Infection, 1947 1. A brief introduction has been given to the conglutination reaction. 2. The technique used by us for carrying out the conglutinating complement absorption test has been described in detail and compared with that used for the haemolytic complement ...
N. Hole, R. Coombs
semanticscholar +1 more source
Ubiquitination of transcription factors in cancer: unveiling therapeutic potential
Molecular Oncology, EarlyView.In cancer, dysregulated ubiquitination of transcription factors contributes to the uncontrolled growth and survival characteristics of tumors. Tumor suppressors are degraded by aberrant ubiquitination, or oncogenic transcription factors gain stability through ubiquitination, thereby promoting tumorigenesis.
Dongha Kim, Hye Jin Nam, Sung Hee Baek
wiley +1 more source
Clinical investigation and management of Brucella suis seropositive dogs: A longitudinal case series
Journal of Veterinary Internal Medicine, 2023 Background Brucellosis in dogs caused by Brucella suis is an emerging zoonotic disease. Objectives To document clinical characteristics, serology, microbiology, and clinical response to treatment in B. suis‐seropositive dogs.
Catherine C. Kneipp +8 more
doaj +1 more source
Jurnal Medik Veteriner, 2021 The purpose of this research was to detect Brucellosis in female dairy cattle in Turen District, Malang Regency. A total of 78 samples were used in this research taken from 351 total population of female dairy cattle that have been calculated based on ...
Imbi Kusumastuti +5 more
doaj +1 more source
The colloidal properties of human serum: with special reference to the changes that take place in syphilis [PDF]
, 1928 It is well known that as a result of syphilitic infection various changes occur in blood sera, and that for the detection of these changes several reactions have been elaborated some of which are of great clinical importance. Of these the complement
Voge, Cecil I. B.
core
THE IMMUNOLOGICAL RESPONSE TO INFLUENZA VIRUS INFECTION AS MEASURED BY THE COMPLEMENT FIXATION TEST
Journal of Experimental Medicine, 1943 A quantitative complement fixation test with influenza immune sera and virus antigens obtained from allantoic fluid is described. The method utilizes a photoelectric densitometer which provides a simple, objective, and accurate determination of the ...
W. Friedewald
semanticscholar +1 more source
A potential tumor suppressor role of PLK2 in glioblastoma
FEBS Open Bio, EarlyView.PLK2 was consistently downregulated in GBM tissues. Overexpression of PLK2 in GBM cell lines U87MG and U251 reduced their tumorigenic potential and enhanced cell cycle arrest and apoptosis. Suggesting that PLK2 overexpression could potentially be leveraged as a therapeutic strategy to inhibit tumor progression and enhance apoptosis, providing new ...
Xiangping Xia +5 more
wiley +1 more source