Results 181 to 190 of about 303,951 (335)
Application of a Quantitative Complement-Fixation Test to the Serum Diagnosis of Typhus Fever [PDF]
Florence M. Varley, Frederick R. Weedon
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hESCs‐derived Organoids Achieve Liver Zonation Features through LSEC Modulation
This article addresses the absence of zonation features in current organoid models by co‐culturing human embryonic stem cell‐derived hepatocytes with liver sinusoidal endothelial cells exhibiting distinct zonal characteristics. It demonstrates that differential WNT2 signaling from endothelial cells modulates hepatocyte zonation and metabolic functions,
Yuying Zhang+13 more
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Epileptiform Activity and Seizure Risk Follow Long‐Term Non‐Linear Attractor Dynamics
This study leverages the HAVOK framework to model long‐term, nonlinear attractor dynamics underlying epileptiform activity and seizure risk in epilepsy patients. By identifying key forcing mechanisms driving chaotic transitions, the findings improve seizure risk forecasting over multi‐day cycles and provide a pathway for personalized, data‐driven ...
Richard E Rosch+4 more
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Observations on the Sensitivity of the Haemolytic System in Complement-fixation Tests [PDF]
Hannah Rice
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Induction of Fc-dependent functional antibodies against different variants of SARS-CoV-2 varies by vaccine type and prior infection. [PDF]
Harris AW+12 more
europepmc +1 more source
Tirzepatide, a dual GIP/GLP‐1 receptor agonist for diabetes, suppresses colorectal cancer growth by targeting glucose metabolism. It inhibits cancer cell proliferation, promotes apoptosis, and induces tumor regression. It reduces glucose uptake and destabilizes HIF‐1α for degradation to downregulate PFKFB3/PFK‐1 enzymes, thus contributing to the ...
Yikai Zhang+11 more
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COVID-19-Associated Cold Agglutinin Syndrome and Hemophagocytosis in a Patient with Monoclonal Gammopathy of Undetermined Significance. [PDF]
Yu Y, Yang K.
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Ca2+/calmodulin‐dependent kinase II (CaMKII) activation is likely driven by oxidative stress, particularly excessive reactive oxygen species (ROS) production. This study identifies P21‐activated kinase 2 (Pak2) as a novel regulator of ROS‐induced CaMKII activation and abnormal Ca2⁺ dynamics in acute adrenergic and chronic pressure‐overload stressed ...
Tao Li+21 more
wiley +1 more source