Results 71 to 80 of about 490,007 (257)
Apolipoprotein E related Co-Morbidities and Alzheimer’s disease [PDF]
The primary goal of advancement in clinical services is to provide a health care system that enhances an individual’s quality of life. Incidence of diabetes mellitus, cardiovascular disease and associated dementia coupled with the advancing age of the ...
Akiyama +147 more
core +1 more source
Modulation of apoprotein E secretion in response to receptor-mediated endocytosis in resident and inflammatory macrophages. [PDF]
We have determined the effect of various endocytic ligands on the secretion of ApoE by macrophages. ApoE was a major secreted protein of resident macrophages, but BCG-activated macrophages secreted little ApoE and periodate-elicited macrophages secreted ...
Takemura, R, Werb, Z
core +2 more sources
Alexandra Francian,1 Kristine Mann,1,2 Max Kullberg1 1WWAMI Medical Education Program, 2Department of Biological Sciences, University of Alaska Anchorage, Anchorage, AK, USA Abstract: Antitumor immunity in cancer patients is heavily modulated by cells ...
Francian A, Mann K, Kullberg M
doaj
The complement system participates in the pathogenesis of many diseases. Complement activation produces several active protein complexes and peptides, including the terminal C5b-9 complexes.
Michal Lusthaus +3 more
doaj +1 more source
Enhancement of platelet response to immune complexes and IgG aggregates by lipid A-rich bacterial lipopolysaccharides. [PDF]
The effect of the common lipid moiety of bacterial LPS on secretion from washed human platelets has been studied. The lipid A-rich LPS of S. minnesota R595 and a lipid A preparation both potentiated platelet serotonin secretion in response to IgG ...
Ginsberg, MH, Henson, PM
core +1 more source
Complement Receptors and Their Role in Leukocyte Recruitment and Phagocytosis [PDF]
Sofie Vandendriessche +3 more
openalex +1 more source
Cancer immunotherapy has made remarkable clinical advances in recent years. Antibodies targeting the immune checkpoint receptors PD-1 and CTLA-4 and adoptive cell therapy (ACT) based on ex vivo expanded peripheral CTLs, tumor infiltrating lymphocytes ...
Yu Wang, Hui Zhang, You-Wen He
doaj +1 more source
A homing receptor-IgG chimera as a probe for adhesive ligands of lymph node high endothelial venules. [PDF]
The binding of lymphocytes to high endothelial venules (HEV) within peripheral lymph nodes (pln) is thought to be mediated by a lectinlike adhesion molecule termed the pln homing receptor (pln HR). The cloning and sequencing of cDNAs encoding both murine
Fennie, C +5 more
core
Identification of novel molecular signatures of IgA nephropathy through an integrative -omics analysis [PDF]
IgA nephropathy (IgAN) is the most prevalent among primary glomerular diseases worldwide. Although our understanding of IgAN has advanced significantly, its underlying biology and potential drug targets are still unexplored.
Cisek, Katryna +11 more
core +2 more sources
Identification of the Kna/Knb polymorphism and a method for Knops genotyping [PDF]
BACKGROUND: DNA mutations resulting in the McCoy and Swain-Langley polymorphisms have been identified on complement receptor 1 (CR1)—a ligand for rosetting of Plasmodium falciparum-infected RBCs.
Daniels +17 more
core +1 more source

