Results 221 to 230 of about 2,103,871 (307)

In Vivo‐Like Scaffold‐Free 3D In Vitro Models of Muscular Dystrophies: The Case for Anchored Cell Sheet Engineering in Personalized Medicine

Advanced Healthcare Materials, EarlyView.
The scaffold‐free Anchored Cell Sheet Engineering platform is used to create three‐dimensional (3D) in vitro models of skeletal muscle tissue that replicate key features of Duchenne and Myotonic dystrophies. These personalized tissue models, validated by histological, immunostaining, and proteomics analyses, accurately mimic disease phenotypes and ...
Alireza Shahin‐Shamsabadi, John Cappuccitti   +1 more
wiley   +1 more source

Transcriptomics and proteomics reveal associations between myometrium and intrauterine adhesions. [PDF]

BMC Womens Health
Xu X, Guo K, Zhao P, Zhang X, Zhao P, Sun X, Zhang M, Tian Y, Fen L, Zheng J, Huang X.   +10 more
europepmc   +1 more source

Biomimetic Glycosaminoglycan‐Analog Hydrogel for Improved Embolization of Aneurysms: Environment‐Selective Swelling

Advanced Healthcare Materials, EarlyView.
Biomimetic glycosaminoglycan analog hydrogels exhibit suitable and robust mechanical properties, as well as hemocompatibility and biocompatibility, making them ideal for the embolization of intracranial aneurysms. Notably, the hydrogel's environment‐selective swelling properties enable complete blockage of the aneurysm cavity while preventing ...
Sarit S. Sivan, Iris Bonshtein, Maria Khoury, Yevgeniy Kreinin, Dmitry Korneyev, Tirosh Mekler, Sumaya Kaiyal, Iris Sonia Weitz, Netanel Korin   +8 more
wiley   +1 more source

Peptidomics characteristics of pediatric sepsis. [PDF]

Sci Rep
Yan H, Li X, Luo T, Zeng X, Li X, Xie L, Wang X, Yang Y, Zhang X, Huang J, Liu P, Luo L, Cao J, Zhou H, Lu X, Xiao Z.   +15 more
europepmc   +1 more source

Recent Applications of Mesoporous Silica Nanoparticles in Gene Therapy

Advanced Healthcare Materials, EarlyView.
The review summarizes the synthesis of mesoporous silica nanoparticles (MSNs) with modifiable surface properties, functionalization strategies, mechanism of therapeutic payload release, and current applications in gene therapy, focusing on their capabilities in the targeted delivery of therapeutic nucleic acids, CRISPR‐Cas systems, and other genetic ...
Tamanna Binte Huq, Punnya Anil Kumar Jeeja, Sudip Kumar Dam, Sabya Sachi Das, Juan L. Vivero‐Escoto   +4 more
wiley   +1 more source

Complement-mediated enhancement of SARS-CoV-2 antibody neutralisation potency in vaccinated individuals. [PDF]

Nat Commun
Mellors J, Dhaliwal R, Longet S, Tipton T, OCTAVE Consortium, OPTIC Consortium, Barnes E, Dunachie SJ, Klenerman P, Hiscox J, Carroll M.   +10 more
europepmc   +1 more source

Inorganic Nanomaterials Meet the Immune System: An Intricate Balance

Advanced Healthcare Materials, EarlyView.
Metal nanomaterials influence the immune responses, such as cytokine production and T‐cell activity. Unintended immune modulation can have significant consequences while its fine‐tuning may transform the oncology care. Within this review, a critical analysis is offered regarding the nano/immune‐interaction and suggests the future research directions to
Gloria Pizzoli, Marco Gargaro, Giuliana Drava, Valerio Voliani   +3 more
wiley   +1 more source

The role of complement in tumor immune tolerance and drug resistance: a double-edged sword. [PDF]

Front Immunol
Yang R, Fu D, Liao A.
europepmc   +1 more source

Harnessing Nanohybridized Niclosamide for Precision Mpox Therapeutics

Advanced Healthcare Materials, EarlyView.
This study investigates the potential of nanohybridized niclosamide as a therapeutic agent for Mpox, focusing on enhanced bioavailability, improved antiviral efficacy, and controlled drug release achieved through nanoengineering. The research emphasizes significant advancements in formulation strategies, mechanistic insights, and therapeutic outcomes ...
N. Sanoj Rejinold, Geun‐woo Jin, Jin‐Ho Choy   +2 more
wiley   +1 more source

mSphere of Influence: Complement activity beyond systemic circulation-implications in the context of infections. [PDF]

mSphere
Desai JV.
europepmc   +1 more source