Results 1 to 10 of about 42 (40)
Reductionism Debate in Molecular Biology: Max Delbrück’s Complementarity Approach
Studia Historiae Scientiarum, 2023 In this paper, I address Max Delbrück’s conceptual and experimental importance for molecular biology (henceforth MB) origins. In particular, his complementarity approach and its anti-reductive implications on the (epistemic) reductionism debate in MB.
Vito Balorda
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PLoS ONE, 2023 Protein tandem repeats (TRs) are motifs comprised of near-identical contiguous sequence duplications. They are found in approximately 14% of all proteins and are implicated in diverse biological functions facilitating both structured and disordered ...
James A. Davey, Natalie K. Goto
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Frontiers in Molecular Biosciences, 2022 Many factors influence biomolecule binding, and its assessment constitutes an elusive challenge in computational structural biology. In this aspect, the evaluation of shape complementarity at molecular interfaces is one of the main factors to be ...
Alfredo De Lauro +7 more
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Phytool, a ShinyApp to homogenise taxonomy of freshwater microalgae from DNA barcodes and microscopic observations [PDF]
Metabarcoding and Metagenomics, 2021 Methods for biomonitoring of freshwater phytoplankton are evolving rapidly with eDNA-based methods, offering great complementarity with microscopy. Metabarcoding approaches have been more commonly used over the last years, with a continuous increase in ...
Alexis Canino +4 more
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iScience, 2020 Summary: HOTAIR was proposed to regulate either HoxD cluster genes in trans or HoxC cluster genes in cis, a mechanism that remains unclear. We have identified a 32-nucleotide conserved noncoding element (CNE) as HOTAIR ancient sequence that likely ...
Chirag Nepal +7 more
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Oligoribonucleotide (ORN) interference-PCR (ORNi-PCR): a simple method for suppressing PCR amplification of specific DNA sequences using ORNs. [PDF]
PLoS ONE, 2014 Polymerase chain reaction (PCR) amplification of multiple templates using common primers is used in a wide variety of molecular biological techniques. However, abundant templates sometimes obscure the amplification of minor species containing the same ...
Naoki Tanigawa +2 more
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Scientific Reports, 2022 What are the molecular determinants of protein–protein binding affinity and whether they are similar to those regulating fold stability are two major questions of molecular biology, whose answers bring important implications both from a theoretical and ...
Fausta Desantis +4 more
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N-glycoproteome of E14.Tg2a mouse embryonic stem cells. [PDF]
PLoS ONE, 2013 E14.Tg2a mouse embryonic stem (mES) cells are a widely used host in gene trap and gene targeting techniques. Molecular characterization of host cells will provide background information for a better understanding of functions of the knockout genes. Using
Bingyun Sun +9 more
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Computational and Structural Biotechnology Journal, 2020 Protein-protein interactions regulate almost all cellular functions and rely on a fine tune of surface amino acids properties involved on both molecular partners.
Lorenzo Di Rienzo +6 more
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Toxicon: X, 2020 Biological systems are inherently hierarchical. Consequently, any field which aims to understand an aspect of biology holistically requires investigations at each level of the hierarchy of life, and venom research is no exception.
Kevin Arbuckle
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