Results 141 to 150 of about 243,208 (262)

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

Dietary and non-dietary complementary and alternative medicine use in Saudi Arabia: the differential role of associated factors. [PDF]

BMC Complement Med Ther
Da'ar OB, Alkaiyat M, Alsadoun FA, Alshehri SGM, Hakeem AH, Almazroa HR, Alrajhi MNA, Bin Saleh FS, Almusalam AA, Algannas N, Alzaid FN, Almanea AE, Jazieh AR.   +12 more
europepmc   +1 more source

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

FEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo, Keisuke Okuno, Shuichi Watanabe, Sakiko Oba, Hiroyasu Kagawa, Masanori Tokunaga, Daisuke Ban, Yusuke Kinugasa   +7 more
wiley   +1 more source

Perception and Use of Complementary and Alternative Medicine among Acne Vulgaris Patients. [PDF]

Skin Appendage Disord
Albash LA, Alali OA, Alkhars OZ, Almulhim NA, Albaqshi AA, Alsakkak HA, Almarri FH, Alsuwailem OA, Alalawi AA, Alojail HY, Alwesaibie HS.   +10 more
europepmc   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Complementary and alternative medicine use among elderly cancer patients: a cross-sectional study in South Korea. [PDF]

Front Oncol
Chang H, Choi SJ, Im HB, Choi D, Han D.
europepmc   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

Utilization of Complementary and Alternative Medicine Among Patients with Cancer: A Cross-Sectional Study. [PDF]

Inquiry
Paudel S, Pathak N, Shrestha R, Regmi P, Sapkota S, Shrestha S.   +5 more
europepmc   +1 more source

A yeast model of 5‐oxoproline accumulation reveals a general toleration to 5‐oxoproline

FEBS Open Bio, EarlyView.
Using a yeast model, we show that even high accumulation of 5‐oxoproline causes only mild cellular stress and does not trigger oxidative stress. Instead, cells adapt by activating efflux pumps and diverse protective pathways, suggesting that previously proposed harmful effects of 5‐oxoproline may arise from indirect metabolic imbalances rather than the
Pratiksha Dubey, Vaishnavi Sanjayan, Praveen Singh, Shantanu Sengupta, Anand Kumar Bachhawat   +4 more
wiley   +1 more source

Use of Complementary and Alternative Medicine in the Management of Breast Cancer.

JAMA Netw Open
Ayoade OF, Caturegli G, Canavan ME, Resio BJ, Berger ER, Boffa DJ.   +5 more
europepmc   +1 more source