Results 121 to 130 of about 282,933 (302)

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Communication between Norwegian Pakistani patients and healthcare providers about traditional and complementary medicine: a qualitative study

International Journal of Qualitative Studies on Health & Well-Being
Purpose Norwegian Pakistanis use traditional and complementary medicines (T&CM) to promote well-being and treat illnesses. Effective communication between T&CM users and healthcare providers (HCPs) about these practices is essential for patient safety ...
Saliha Khalid, Trine Stub, Agnete Egilsdatter Kristoffersen, Christine Råheim Borge, Lise-Merete Alpers   +4 more
doaj   +1 more source

Defining research priorities in complementary medicine in oncology

, 2012
Objectives: The high usage of complementary and alternative medicines (CAM) by cancer patients is increasing, despite limited research available to support their use.
Bensoussan, Alan (R7273), Robotin, Monica C., Holliday, Cath   +2 more
core   +1 more source

Prospecting the protein design landscape

FEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona, Katharina T. Stonig, Jens Meiler, Clara T. Schoeder, Monica L. Fernández‐Quintero   +4 more
wiley   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Risk and efficacy in biomedical media representations of herbal medicine and complementary and alternative medicine (CAM)

, 2011
The objective of the research was to map the discourse about herbal medicine in Australia’s primary medical journal, the Medical Journal of Australia, over 4 decades. Manifest content analysis of 148 articles about herbal or complementary and alternative
Lewis, Monique, Lewis, M, Monique Lewis
core   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Exploring men’s cancer journeys in Norway: a comprehensive survey on diet, supplements, and use of complementary and alternative therapies

BMC Complementary Medicine and Therapies
Background Each year, over 20,000 men are diagnosed with cancer in Norway, and approximately 150,000 men who have previously been diagnosed with cancer are currently alive. Many of these cancer survivors encounter a range of challenges, including fatigue,
Agnete E. Kristoffersen, Kiwumulo Nakandi, Arne Johan Norheim, Mona Bjelland, Jorunn V. Nilsen, Eran Ben-Arye   +5 more
doaj   +1 more source

Pulse Diagnosis in Thai Traditional Medicine: Comparing Tri-Dhātu Characteristics in Each Innate Body Element between Experts and Device

Journal of Health Research
Background: Pulse diagnosis in Thai Traditional Medicine (TTM) evaluates the balance of the Tri-Dhātu—Vata, Pitta, and Semha—and their interaction with innate body elements (Dhātu Chao Ruean; DCR).
Athippat Tantiwongsekunakorn, Suksalin Booranasubkajorn, Thanaphak Chaopeerapong, Angkana Apichartvorakit, Pravit Akarasereenont   +4 more
doaj   +1 more source

Regulation of complementary medicine practitioners in Australia : Chinese medicine as a case example

, 2002
Complementary and alternative medicine (CAM) forms a significant part of the health economy. CAM practices are under increased scrutiny from consumers, clinicians, scientists and regulators.
Bensoussan, Alan, Carlton, Anne-Louise
core