Results 41 to 50 of about 2,044,716 (227)
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Cyclic Codes over a Non-Local Non-Unital Ring
MathematicsWe study cyclic codes over the ring H of order 4 and characteristic 2 defined by generators and relations as H=⟨a,b∣2a=2b=0,a2=0,b2=b,ab=ba=0⟩. This is the first time that cyclic codes over a non-unitary ring are studied.
Adel Alahmadi +2 more
doaj +1 more source
Structural and biochemical analysis of a B12 superbinder
FEBS Letters, EarlyView.BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
Constacyclic and Linear Complementary Dual Codes Over Fq + uFq [PDF]
, 2020 This article discusses linear complementary dual (LCD) codes over ℜ = Fq+uFq(u2=1) where q is a power of an odd prime p. Authors come up with a new Gray map from ℜn to F2nq and define a new class of codes obtained as the gray image of ...
Prakash, Om +2 more
core +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Column cyclic rank metric codes and linear complementary dual rank metric codes
, 2023 We introduce and study column cyclic rank metric (CCRM) codes over finite fields. We present natural questions for the existence and characterization of CCRM codes.
Özbudak, Ferruh +3 more
core +1 more source
FEBS Letters, EarlyView.Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise +5 more
wiley +1 more source
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Constructions and Enumerations of Self-Dual and LCD Double Circulant Codes over a Local Ring
MathematicsThe construction of self-dual and linear complementary dual (LCD) codes over finite rings, particularly over semi-local and local structures, is an active area of research due to their algebraic richness and applications in communications and ...
Sami H. Saif
doaj +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source