Results 71 to 80 of about 2,497 (286)

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

On Schur's complement

open access: yesJournal of Combinatorial Theory, Series A, 1973
AbstractA new proof is given for Haynsworth's formula for Schur's complement.
openaire   +3 more sources

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Complementizer doubling and subject extraction in Italo-Romance

open access: yes, 2018
In this article I analyze the complementizer doubling construction attested in some early and modern Italo-Romance varieties, where a preposed (clausal or non clausal) constituent associated to the selected clause appears in the embedded left periphery ...
Munaro, Nicola, Nicola Munaro
core   +1 more source

Complementizer selection and the properties of complement clauses in German [PDF]

open access: yes, 2004
Complement clauses in German can have a lexical complementizer when they are finite, but they must not have one when they are non-finite. I will argue that this distribution follows from the referential properties of the sentential complement.
Wöllstein, Angelika   +1 more
core   +1 more source

Yoruba pe and ki verbs or complementizers

open access: yesStudies in African Linguistics, 1991
This paper discusses the Yoruba items Pe and K£. These items have sometimes been analyzed as verbs and sometimes as complementizers. Thus their status has not been clearly established. In this paper, we look at the various structures in which these items
Adenike Lawal
doaj   +3 more sources

AGAINST THE NULL COMPLEMENTIZER ANALYSIS OF JAPANESE RELATIVE CLAUSES [PDF]

open access: yes
In this paper, I argued that relative clauses in Japanese are IPs, contrary to the proposal that they are CPs headed by a null complementizer. I assumed that the lack of CP is responsible for the inapplicability of embedded topicalization in relative ...
Taguchi, S
core   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

The complementizer function of type-nouns in ad hoc concept construction: Evidence from Italian and Russian

open access: yes, 2023
The purpose of this study is to explore the semantic and pragmatic aspects of the complementizer function of type-nouns (cognates of type) in Italian and Russian and their role in the construction of ad hoc concepts. Italian tipo and Russian tipa have
Benigni V.
core   +1 more source

Fishing for complements [PDF]

open access: yesBlood, 2016
In this issue of Blood , [Jodele et al][1][1][2] build upon earlier work on the role of complement in the pathophysiology[2][3] and therapy[3][4] of transplant-associated thrombotic microangiopathy (TA-TMA) by exploring genetic predisposition for developing this complication.
openaire   +2 more sources

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