Results 41 to 50 of about 501 (234)

The Agreement Measure γcat a Complement to γ Focused on Categorization of a Continuum [PDF]

open access: yesComputational Linguistics, 2017
Agreement on unitizing, where several annotators freely put units of various sizes and categories on a continuum, is difficult to assess because of the simultaneaous discrepancies in positioning and categorizing. The recent agreement measure γ offers an overall solution that simultaneously takes into account positions and categories.
openaire   +4 more sources

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Biophysical approaches for studying viral entry

open access: yesFEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

The layered internal structure and the external syntax of PP [PDF]

open access: yes, 2001
This thesis examines the properties of spatial (i.e., locational and directional) Ps within the minimalist framework (Chomsky 1995,1998,1999), which has put an ultimate emphasis on economy in terms of derivation and representation. The principal goals of
Ayano, Seiki
core  

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

open access: yesFEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

On the licensing of complementizer agreement with nominals in the left periphery

open access: yesJournal of Linguistics
Abstract This research article examines the licensing of complementizer agreement with nominals (namely thematic subjects and objects) in the left periphery, focusing on data from Jordanian Arabic (JA). It demonstrates that obligatory complementizer agreement with A-bar elements is evident in JA grammar due to the effects of the Agree Identification
Basem Al-Raba’a, Marwan Jarrah
openaire   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

No objections to backward control?

open access: yes, 2009
The aim of this paper is to address two main counterarguments raised in Landau (2007) against the movement analysis of Control, and especially against the phenomenon of Backward Control.
Alexiadou, Artemis   +3 more
core   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

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