Results 61 to 70 of about 8,273 (242)

Challenges in clinical and laboratory diagnosis of androgen insensitivity syndrome: a case report

Journal of Medical Case Reports, 2011
Introduction Androgen is a generic term usually applied to describe a group of sex steroid hormones. Androgens are responsible for male sex differentiation during embryogenesis at the sixth or seventh week of gestation, triggering the development of the ...
Silva Daniela M, Melo Caroline OA, da Cruz Aparecido D   +2 more
doaj   +1 more source

Psychological and family intervention with a person diagnosed with complete androgen insensitivity syndrome

Telangana Journal of Psychiatry, 2023
Complete androgen insensitivity syndrome (CAIS) is a rare condition resulting due to the inability of the cell to respond to the masculine hormone (androgen). Often, CAIS patients identify themselves as female and may experience significant psychological
Mysore Narasimha Vranda, Suresh Badamath, Marita Kadicheeni Paul, Radhakrishnan Vasanthra Cicil, Prakyath Ravindranath Hegde, Adharsa Ajayan, Hari Hara Suchendra, Tshering Lhamu   +7 more
doaj   +1 more source

Clinical, Hormonal and Genetics Features in patients with Androgen Insensitivity Syndrome in Cytogenetic Laboratories in Semarang [PDF]

, 2006
Androgen insensitivity syndrome (AIS) is an X-linked disorder caused by impaired Androgen Receptor (AR) which is encoded in Xq 11-12. In this condition, although the androgen is produced sufficiently, but the peripheral masculinizing effect is blocked ...
Tonang, Alvin
core  

Personalizing therapies over the course of hormone receptor‐positive/HER2‐negative metastatic breast cancer

CA: A Cancer Journal for Clinicians, Volume 76, Issue 1, January/February 2026.
ABSTRACT The hormone receptor (HR)‐positive/human epidermal growth factor receptor 2 (HER2)‐negative breast cancer subtype accounts for most early and metastatic breast cancer (MBC) cases. HR‐positive/HER2‐negative MBC is characterized by a relatively prolonged, although variable, disease course and substantial intertumoral and intratumoral ...
Akshara Singareeka Raghavendra, Senthil Damodaran, Carlos H. Barcenas, Suzanne A. Fuqua, Rachel M. Layman, Debu Tripathy   +5 more
wiley   +1 more source

Androgen and estrogen receptor expression in the developing human penis and clitoris. [PDF]

, 2020
To better understand how the human fetal penis and clitoris grows and remodels, we undertook an investigation to define active areas of cellular proliferation and programmed cell death spatially and temporally during development of human fetal external ...
Baskin, Laurence, Cao, Mei, Cunha, Gerald R, Isaacson, Dylan, Li, Yi, Overland, Maya, Sinclair, Adriane   +6 more
core  

The Concise Guide to PHARMACOLOGY 2025/26: Enzymes

British Journal of Pharmacology, Volume 182, Issue S1, Page S307-S403, December 2025.
The Concise Guide to Pharmacology 2025/26 marks the seventh edition in this series of biennial publications in the British Journal of Pharmacology. Presented in landscape format, the guide provides a comparative overview of the pharmacology of drug target families. The concise nature of the Concise Guide refers to the style of presentation, being clear,
Stephen P. H. Alexander, Doriano Fabbro, Alasdair J. Gibb, Eamonn Kelly, Alistair A. Mathie, Chloe J. Peach, Emma L. Veale, Jane F. Armstrong, Elena Faccenda, Simon D. Harding, Christopher Southan, Jamie A. Davies, Stephanie Annett, Detlev Boison, Kathryn Elisa Burns, Carmen Dessauer, Jürg Gertsch, Nuala Ann Helsby, Angelo A. Izzo, Rennolds Ostrom, Ester Pagano, Andreas Papapetropoulos, Nigel J. Pyne, Susan Pyne, Tracy Robson, Roland Seifert, Johannes‐Peter Stasch, Csaba Szabo, Mario van der Stelt, Albert van der Vliet, Val Watts, Szu Shen Wong   +31 more
wiley   +1 more source

Androgen Receptor Function Links Human Sexual Dimorphism to DNA Methylation [PDF]

, 2013
Sex differences are well known to be determinants of development, health and disease. Epigenetic mechanisms are also known to differ between men and women through X-inactivation in females.
A Bird, A Khattri, Bernhard Korn, BG Choi, C Ober, CJ Brown, D Decaudin, DH Abbott, DK Mishra, EG Boerma, EN Gal-Yam, F de Medeiros, Felix G. Riepe, Frans Verheijen, HM Scott, I Savic, IA Hughes, Ieuan Hughes, J Lambert, J Simard, JI Martín-Subero, JT Chang, K Hogg, K Kaunisto, K Nohara, LL Xu, M Appari, M Hines, M Jürgensen, M Weber, M Welsh, Mahesh Appari, Martine Cools, MB Stadler, MD Anway, MD Anway, MD Anway, MD Anway, ME Soto, MK Skinner, O Ammerpohl, Olaf Hiort, Ole Ammerpohl, Paul-Martin Holterhus, PM Holterhus, PM Holterhus, PM Holterhus, PM Holterhus, PP Luedi, Ralf Werner, RE Thurman, Reiner Siebert, RM Brena, RM Novick, S Augui, S Bens, S Burgdorf, S Do Carmo, SE Nada, SE Trasino, SJ Clark, Stenvert L. S. Drop, Susanne Bens, Trevor Bunch, V Padmanabhan, Wolfgang Wagner, Y Chi, YH Jiang, YT Konttinen, Yvonne van der Zwan   +69 more
core   +10 more sources

Sucessful Transition in Rare Endocrine Diseases: Patient Experiences in a French Reference Centre

Clinical Endocrinology, Volume 103, Issue 6, Page 833-840, December 2025.
ABSTRACT Objective This study aimed to evaluate the experiences of patients who had a joint endocrinology consultation for transition to adult care at Marseille university hospitals between 2010 and 2020, focusing on patient follow‐up, satisfaction, difficulties, and expectations.
Karine Aouchiche, Thierry Brue, Emeline Marquant, Gilbert Simonin, Sarah Castets, Rachel Reynaud, Frederique Albarel   +6 more
wiley   +1 more source

Why Are Autism Spectrum Conditions More Prevalent in Males? [PDF]

, 2011
Autism Spectrum Conditions (ASC) are much more common in males, a bias that may offer clues to the etiology of this condition. Although the cause of this bias remains a mystery, we argue that it occurs because ASC is an extreme manifestation of the male ...
Ashwin, Emma, Auyeung, Bonnie, Baron-Cohen, Simon, Chakrabarti, Bhismadev, Knickmeyer, Rebecca, Lombardo, Michael V.   +5 more
core   +4 more sources

Germ cell and other tumors in individuals with differences in sex development

CA: A Cancer Journal for Clinicians, Volume 75, Issue 6, Page 587-601, November/December 2025.
Abstract Approximately one in 3500 to one in 5100 live‐born infants have atypical external genital development, known as differences in sex development (DSD). In 2005, an expert consensus conference thoroughly reviewed aspects of health care for individuals with DSD.
Selma Feldman Witchel, Miguel Reyes‐Múgica   +1 more
wiley   +1 more source