Results 111 to 120 of about 683,768 (364)
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
Molecular Oncology, EarlyView.PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source
Coupled fixed point results on metric spaces defined by binary operations
Karpatsʹkì Matematičnì Publìkacìï, 2018 In parallel with the various generalizations of the Banach fixed point theorem in metric spaces, this theory is also transported to some different types of spaces including ultra metric spaces, fuzzy metric spaces, uniform spaces, partial metric spaces, $
A. Karami +3 more
doaj +1 more source
FEBS Open Bio, EarlyView.Light activation of the photoswitchable cannabinoid ligand azo‐HU308 triggers Ca2+ influx in pancreatic β‐cells through TRPC channels, independent of CB2 cannabinoid receptors. This reveals a non‐GPCR pathway for cannabinoid modulation of β‐cell Ca2+ dynamics and establishes azo‐HU308 as an optical tool to study cannabinoid signaling through TRP ...
Alexander E. G. Viray, James A. Frank
wiley +1 more source
Rigidity for the logarithmic Sobolev inequality on complete metric measure spaces [PDF]
, 2023 Franciele Conrado
openalex +1 more source
Completions of partial metric spaces
Topology and its Applications, 2015 A partial metric space which was defined by \textit{S. G. Matthews} in his article [``Partial metric topology'', in: Papers on general topology and applications. Papers from the 8th summer conference at Queens College, New York, NY, USA, June 18--20, 1992. New York, NY: The New York Academy of Sciences.
Ge, Xun, Lin, Shou
openaire +1 more source
FEBS Open Bio, EarlyView.This research protocol outlines a workflow for nuclear magnetic resonance (NMR)‐based metabolomics in the agri‐food sector. Using two case studies—strawberry leaves (solid matrix) and wine (liquid matrix)—it details the procedures for sample preparation, data acquisition, and processing.
Andrea Fernández‐Veloso +4 more
wiley +1 more source
ATP13A2 is involved in intracellular polyamine transport in lung epithelial cells
FEBS Open Bio, EarlyView.Spermidine transport in lung epithelial cells involves the polyamine transporter ATP13A2. Cell proliferation is associated with the upregulation of ATP13A2. Polyamines are present in all living cells and are implicated in various crucial cellular processes such as proliferation, apoptosis and autophagy.
Yuta Hatori +8 more
wiley +1 more source
Generalizations of Caristi Kirk's Theorem on Partial Metric Spaces
Fixed Point Theory and Applications, 2011 In this article, lower semi-continuous maps are used to generalize Cristi-Kirk's fixed point theorem on partial metric spaces. First, we prove such a type of fixed point theorem in compact partial metric spaces, and then generalize to complete partial ...
Karapinar Erdal
doaj
Common fixed point theorems for weakly increasing mappings on ordered orbitally complete metric spaces [PDF]
, 2012 Hui-Sheng Ding +2 more
openalex +1 more source