Recent Advances in Top‐Down Proteomics for Single‐Cell Research
ABSTRACT Individual cells have distinctive molecular characteristics, including biologically relevant proteoforms. Although single‐cell (SC) molecular omics offer unprecedented insights into cellular heterogeneity and function, the characterization of proteoforms in SCs remains an uncharted territory.
Jake A. Melby, Pei Su, Fabio P. Gomes
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Complete mitochondrial sequencing reveals the horizontal transfer and gene rearrangement of <i>Passiflora edulis</i>. [PDF]
Teng Y +8 more
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Through network pharmacology and molecular docking, it has been discovered that CA can target MAOB, among other proteins, to exert a therapeutic effect in IBS. In vivo, CA lowered visceral hypersensitivity, anxiety and depression‐like behaviors, and fecal water content, highlighting its therapeutic potential for IBS via anti‐inflammatory pathways ...
Qingyang Yu +4 more
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Characterization and comparative analysis of the complete mitochondrial genome of <i>Ferula sinkiangensis</i> (K. M. Shen, 1975) (Apiales: Apiaceae). [PDF]
Deng X +5 more
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Climate extremes threaten the sustainability of cranberry production, a culturally and economically important North American crop. This study demonstrates that wild cranberries (Vaccinium oxycoccos) harbor genetic variation that may enhance cold stress resilience when introduced into cultivated cranberry through hybridization.
Audrey Dickinson +5 more
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Origins of Avian Hyperactive Mitochondria, Genome Compaction, and Air-Sac Physiology in Early Theropods During the Carnian Pluvial Episode. [PDF]
Satoh T.
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Gene turnover in the common ancestor of all C4 grasses
Understanding how plants evolve more efficient photosynthesis is important in a warming world where improving crop productivity and resilience is a global priority. By generating the first reference genomes for an early‐diverging group of grasses called the Aristidoideae, we were able to reconstruct the genetic makeup of the last common ancestor of all
Lara Pereira +6 more
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Structure and multipartite genome architecture of the mitochondrial genome in the endangered medicinal plant <i>Fritillaria taipaiensis</i> P. Y. Li. [PDF]
Xu +7 more
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ABSTRACT Proteins are built from modular domains that serve as fundamental units of structure and evolution. While individual domains have been extensively cataloged, their collective distribution across the lineages of life has remained poorly resolved.
Rui Guo +5 more
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The multichromosomal structure evolution of <i>Dendrobium</i> mitogenomes and new insights into interrelationships of recently radiated tribes in Epidendroideae (Orchidaceae). [PDF]
Wang M +10 more
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