Results 101 to 110 of about 307,893 (296)

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

Analysis of complete mitochondrial genome of Etisus anaglyptus (Arthropoda, Decapoda, Xanthidae) with phylogenetic consideration

Mitochondrial DNA. Part B. Resources, 2018
The complete mitochondrial genome is sequenced and analyzed from a xanthid crab Etisus anaglyptus, which is the first complete mitochondrial genome for the genus. The mitochondrial genome length of E.
Mustafa Zafer Karagozlu, Thinh Do Dinh, Van Quan Nguyen, Chang-Bae Kim   +3 more
doaj   +1 more source

The complete mitochondrial genome of Coriandrum sativum

Mitochondrial DNA. Part B. Resources, 2021
Using Oxford Nanopore and Illumina sequencing technologies, we reported the first complete mitochondrial genome of the important medicinal and edible plant Coriandrum sativum.
Yiheng Wang, Qingkuo Lan, Xin Zhao, Luping Wang, Wancong Yu, Bo Wang, Yong Wang   +6 more
doaj   +1 more source

Archaic mitochondrial DNA inserts in modern day nuclear genomes

, 2019
Traces of interbreeding of Neanderthals and Denisovans with modern humans in the form of archaic DNA have been detected in the genomes of present-day human populations outside sub-Saharan Africa.
Bücking, R., Cox, M., Hudjashov, G., Saag, L., Stoneking, M., Sudoyo, H.   +5 more
core   +1 more source

The reduced genome of the parasitic Microsporidian Enterocytozoon bieneusi lacks genes for core carbon metabolism [PDF]

, 2010
© The Authors, 2010. This article is distributed under the terms of the Creative Commons Attribution-Noncommercial 2.5 License. The definitive version was published in Genome Biology and Evolution 2 (2010): 304, doi:10.1093/gbe/evq022.Reduction of ...
Keeling, P. J., Corradi, N., Morrison, H. G., Haag, K. L., Ebert, Dieter, Weiss, L. M., Akiyoshi, D. E., Tzipori, S.   +7 more
core   +2 more sources

Complete mitochondrial genome sequence of Parumbrosa polylobata [PDF]

Mitochondrial DNA Part B, 2019
The complete mitochondrial genome sequences of giant jellyfish Parumbrosa polylobata, a scyphozoan species inhabiting the Yellow Sea cold bottom water in China, is firstly described and analyzed in this research. It is 16,809 bp in length with a linear mitochondrial DNA. The base composition of the genome with A + T bias is 69.7%.
Song Feng, Jianing Lin, Song Sun, Qing Liu   +3 more
openaire   +3 more sources

Unraveling the Molecular Mechanisms of Glioma Recurrence: A Study Integrating Single‐Cell and Spatial Transcriptomics

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Glioma recurrence severely impacts patient prognosis, with current treatments showing limited efficacy. Traditional methods struggle to analyze recurrence mechanisms due to challenges in assessing tumor heterogeneity, spatial dynamics, and gene networks.
Lei Qiu, Yinjiao Fei, Jiaxuan Ding, Kexin Shi, Jinyan Luo, Yuchen Zhu, Xingjian Sun, Gefei Jiang, Yuandong Cao, Weilin Xu, Shu Zhou   +10 more
wiley   +1 more source

Complete mitochondrial genome of a Siberian Crane (Grus leucogeranus)

Mitochondrial DNA. Part B. Resources, 2018
The complete mitochondrial genome (mtDNA) of hemocyte from Siberian Crane (Grus leucogeranus) was sequenced using high-throughput genetic sequencing, and mitochondrial genome was assembled using MITObim tools according complete mitochondrial genome of ...
Tong Wang, Hongcheng Wang, Zhongbao Zhao, Zongtao Wang, Liqiang Mu, Hongxian Yu   +5 more
doaj   +1 more source

Phylogeny of Prokaryotes and Chloroplasts Revealed by a Simple Composition Approach on All Protein Sequences from Complete Genomes Without Sequence Alignment [PDF]

, 2005
The complete genomes of living organisms have provided much information on their phylogenetic relationships. Similarly, the complete genomes of chloroplasts have helped to resolve the evolution of this organelle in photosynthetic eukaryotes.
C Lemieux, CR Woese, CR Woese, D Sankoff, DH Moreira, E Chatton, E Mayr, E Pennisi, F Tekaia, FitchWM, GI McFadden, GI McFadden, GW Stuart, GW Stuart, J Adachi, J Las Rivas De, J Lin, J Qi, J Qi, J.Q. Deng, JA Eisen, JD Palmer, JR Brown, K.H. Chu, KH Chu, L.Q. Zhou, M Li, M Turmel, M Turmel, MA Ragan, MW Gray, MW Gray, N Saitou, O Weiss, RF Doolittle, RF Doolittle, RL Charlebois, RS Gupta, S.C. Long, ST Fitz-Gibbon, SV Edwards, V.V. Anh, VL Stirewalt, W Martin, W Martin, W Martin, Z.G. Yu, ZG Yu, ZG Yu, ZG Yu, ZG Yu   +50 more
core   +3 more sources

SPG4 and Dementia: Expanding the Clinical Spectrum

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Hereditary spastic paraplegia (HSP) is a group of disorders characterized by progressive spasticity and lower limb weakness, with mutations in SPG4/SPAST being the most common cause. Detailed studies and clinical and molecular comparisons across different populations are missing.
Emanuele Panza, Arun Meyyazhagan, Eliseo Picchi, Gustavo Ribas, Ingrid Faber, Ryosuke Miyamoto, Preethi Basavaraju, Paolo Eusebi, Haripriya Kuchi Bhotla, Mario Stasi, Fabrizio Gaudiello, Francesco Patti, Filippo Maria Santorelli, Marcondes Cavalcante França Jr, José Luiz Pedroso, Orlando Graziani Povoas Barsottini, Hélio Afonso Ghizoni Teive, Peter Henry St George‐Hyslop, Toshitaka Kawarai, Antonio Orlacchio   +19 more
wiley   +1 more source